SCHEMBL8667490

SCHEMBL8667490

C=C(C)CCC1=C(C)C(=O)CC2C(C)(C)CCCC12C

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.59
SULT1E1 P49888 1/20 0.58
MAPKAPK2 P49137 1/20 0.35
CETP P11597 5/20 0.33
CYP19A1 P11511 1/20 0.32
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
PTPN1 P18031 1/20 0.30
CDC25A P30304 1/20 0.30
DUSP3 P51452 1/20 0.30
FDPS P14324 2/20 0.30
GGPS1 O95749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13856769 0.74 TSHR (1.00) TSHRSULT1E1MAPKAPK2CETPALDH1A1
SCHEMBL13446722 0.73 SULT1E1 (1.00) TSHRSULT1E1CETPALDH1A1MAPT
SCHEMBL13446724 0.73 SULT1E1 (0.59) TSHRSULT1E1MAPKAPK2CETPALDH1A1
SCHEMBL14880592 0.73 TSHR (0.56) TSHRSULT1E1CYP19A1ALDH1A1MAPT
SCHEMBL5013008 0.60 ESR1 (0.46) TSHRSULT1E1CETPCYP19A1ALDH1A1
SCHEMBL19770987 0.60 ESR1 (0.46) TSHRSULT1E1CETPCYP19A1ALDH1A1
SCHEMBL5013007 0.60 ESR1 (0.46) TSHRSULT1E1CETPCYP19A1ALDH1A1
SCHEMBL12659027 0.60 PNLIP (0.44) TSHRMAPKAPK2CYP19A1ALDH1A1MAPT
SCHEMBL29403700 0.59 ESR1 (0.48) TSHRSULT1E1CYP19A1ALDH1A1MAPT
SCHEMBL22413404 0.59 ALDH1A1 (0.55) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0634474-B1 Treated labdanum oil, process for preparing the same, novel ketone compound, and perfume composition containing the same KAO CORP (JP) 1998-12-23 EP claimed
EP-0634474-A2 Treated labdanum oil, process for preparing the same, novel ketone compound, and perfume composition containing the same KAO CORPORATION (JP) 1995-01-18 EP claimed
EP-0634474-B1 Treated labdanum oil, process for preparing the same, novel ketone compound, and perfume composition containing the same KAO CORP (JP) 1998-12-23 EP disclosed
EP-0634474-A2 Treated labdanum oil, process for preparing the same, novel ketone compound, and perfume composition containing the same KAO CORPORATION (JP) 1995-01-18 EP disclosed