Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 10/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | HTT | P42858 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 9/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14881170 | 0.86 | MEN1 (0.46) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL14881154 | 0.81 | ALDH1A1 (0.71) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL1761517 | 0.78 | MAPT (0.74) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL19783572 | 0.76 | RAB9A (0.62) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL14881198 | 0.75 | NPC1 (0.60) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL14880926 | 0.74 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL14880928 | 0.74 | RAPGEF4 (0.51) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL2136763 | 0.73 | RAB9A (1.00) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| Bicarbonate SCHEMBL2309733 | 0.72 | NPC1 (0.57) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL4921505 | 0.72 | NPC1 (0.62) | MEN1KMT2AALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013056679-A1 | NOVEL HETEROARYL-AMINO DERIVATIVES | BEIJING HANMI PHARMACEUTICAL CO., LTD (CN) | 2013-04-25 | — | — | WO | disclosed |