Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27995417 | 0.84 | FBP1 (0.41) | MAPTALDH1A1NPSR1TDP1MEN1 | |
| SCHEMBL4649697 | 0.84 | TDP1 (0.40) | LMNAMAPTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL11564194 | 0.84 | ALDH1A1 (0.47) | TSHRLMNAMAPTPTPRCALDH1A1 | |
| SCHEMBL3540428 | 0.82 | ALDH1A1 (0.61) | TSHRLMNAALDH1A1RAB9ATDP1 | |
| SCHEMBL8802211 | 0.80 | AKR1C3 (0.54) | TSHRLMNAMAPTALDH1A1RAB9A | |
| SCHEMBL12472637 | 0.80 | NPC1 (0.50) | LMNAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL8051514 | 0.79 | ALDH1A1 (0.67) | TSHRLMNAMAPTPTPRCALDH1A1 | |
| SCHEMBL6806454 | 0.79 | TDP1 (0.46) | TSHRMAPTALDH1A1TDP1ACHE | |
| SCHEMBL6800906 | 0.78 | TDP1 (0.38) | TSHRMAPTALDH1A1TDP1ACHE | |
| SCHEMBL3299033 | 0.78 | TSHR (0.53) | TSHRLMNAMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780326-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | Vivolux Ab (SE) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013058691-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | VIVOLUX AB (SE) | 2013-04-25 | — | — | WO | disclosed |