Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 10/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21379541 | 0.72 | RXRA (0.35) | DGAT1FFAR1KDM4EALDH1A1 | |
| SCHEMBL23660849 | 0.71 | NUDT1 (0.38) | FFAR1KDM4E | |
| SCHEMBL14880635 | 0.71 | DGAT1 (0.43) | DGAT1FFAR1ALDH1A1 | |
| SCHEMBL9935273 | 0.70 | AAK1 (0.37) | DGAT1FFAR1PTGDR2 | |
| SCHEMBL738509 | 0.68 | GBA1 (0.38) | FFAR1KDM4ERAB9A | |
| SCHEMBL19582928 | 0.68 | RXRA (0.39) | DGAT1KDM4E | |
| SCHEMBL9936166 | 0.68 | DGAT1 (0.35) | DGAT1FFAR1ALDH1A1 | |
| SCHEMBL2185798 | 0.67 | RXRA (0.38) | DGAT1KDM4EALDH1A1 | |
| SCHEMBL13736023 | 0.67 | TSHR (0.52) | KDM4EALDH1A1PTGDR2 | |
| SCHEMBL5208255 | 0.66 | TSHR (0.50) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013056679-A1 | NOVEL HETEROARYL-AMINO DERIVATIVES | BEIJING HANMI PHARMACEUTICAL CO., LTD (CN) | 2013-04-25 | — | — | WO | disclosed |