SCHEMBL14883196

SCHEMBL14883196

C=COCCN(C)CCCN(C)C

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
DNM1 Q05193 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14883124 0.87 CA12 (0.50) CA12CA2CA3CA4CA6
SCHEMBL329408 0.82
SCHEMBL136974 0.82
SCHEMBL329227 0.80 ALDH1A1 (0.46) ALDH1A1TSHRDNM1
SCHEMBL3059214 0.78 ALDH1A1 (0.50) ALDH1A1TSHRDNM1
SCHEMBL8664976 0.78 ALDH1A1 (0.50) ALDH1A1TSHRDNM1
SCHEMBL8661838 0.78 ALDH1A1 (0.50) ALDH1A1TSHRDNM1
SCHEMBL12571535 0.78 PIK3CD (0.48) ALDH1A1TSHRCA12CA2CA3
SCHEMBL1223478 0.77 LMNA (0.35) ALDH1A1
Dimethylamine SCHEMBL6688002 0.76 PRMT3 (0.35) CA12CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10508156-B2 Catalyst compositions and their use for hydrogenation of nitrile rubber ARLANXEO DEUTSCHLAND GMBH (DE) 2019-12-17 US disclosed
US-20180223005-A1 CATALYST COMPOSITIONS AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER ARLANXEO DEUTSCHLAND GMBH (DE) 2018-08-09 US disclosed
US-20180223005-A1 CATALYST COMPOSITIONS AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER ARLANXEO DEUTSCHLAND GMBH (DE) 2018-08-09 US disclosed
EP-2768611-B1 PROCESS FOR HYDROGENATION OF NITRILE RUBBER USING CATALYST COMPOSITIONS COMPRISING A GRUBBS-HOVEYDA TYPE COMPLEX AND A TERMINAL OLEFIN ARLANXEO DEUTSCHLAND GMBH (DE) 2018-08-01 EP disclosed
US-20150126683-A1 CATALYST COMPOSITIONS AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER LANXESS DEUTSCHLAND GMBH (DE) 2015-05-07 US disclosed
US-20150025199-A1 CATALYST COMPOSITIONS AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER ARLANXEO DEUTSCHLAND GMBH (DE) 2015-01-22 US disclosed
WO-2013057289-A2 CATALYST COMPOSITIONS AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER LANXESS DEUTSCHLAND GMBH (DE) 2013-04-25 WO disclosed