Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967698 | 1.00 | CES1 (0.52) | CES1SRCTSHRCES2ALDH1A1 | |
| SCHEMBL12083377 | 0.84 | CES1 (0.50) | CES1SRCTSHRCES2ALDH1A1 | |
| SCHEMBL21310 | 0.81 | CES1 (0.56) | CES1SRCTSHRCES2ALDH1A1 | |
| SCHEMBL9105008 | 0.81 | CES1 (0.56) | CES1SRCTSHRCES2ALDH1A1 | |
| SCHEMBL1606581 | 0.81 | CES1 (0.56) | CES1SRCTSHRCES2ALDH1A1 | |
| SCHEMBL11341422 | 0.81 | CES1 (0.56) | CES1SRCTSHRCES2ALDH1A1 | |
| SCHEMBL8223282 | 0.81 | CES1 (0.46) | CES1CES2MAPTCYP2C19CA1 | |
| SCHEMBL9420249 | 0.81 | LMNA (0.40) | SRCTSHRTDP1POLBCYP3A4 | |
| SCHEMBL14889163 | 0.81 | ALOX15 (0.50) | CES1TSHRCES2ALDH1A1POLB | |
| SCHEMBL14889160 | 0.81 | ALOX15 (0.50) | CES1TSHRCES2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2586769-B1 | METHOD FOR PRODUCING (1R, 2S)-1-AMINO-2-VINYL CYCLOPROPANE CARBOXYLIC ACID ESTER THAT HAS IMPROVED OPTICAL PURITY | KANEKA CORP (JP) | 2019-01-16 | — | — | EP | disclosed |
| CN-102906064-B | The manufacture method of (1R, 2S)-1-amino-2-vinylcyclopropanecaracidlic acidlic ester that optical purity has been improved | KANEKA CORP. (JP) | 2015-07-29 | — | — | CN | disclosed |
| EP-2586769-A1 | METHOD FOR PRODUCING (1R, 2S)-1-AMINO-2-VINYL CYCLOPROPANE CARBOXYLIC ACID ESTER THAT HAS IMPROVED OPTICAL PURITY | KANEKA CORPORATION (JP) | 2013-05-01 | — | — | EP | disclosed |
| CN-102906064-A | Method for producing (1r, 2s)-1-amino-2-vinyl cyclopropane carboxylic acid ester that has improved optical purity | KANEKA CORP | 2013-01-30 | — | — | CN | disclosed |