Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | BAD | Q92934 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967698 | 0.81 | CES1 (0.52) | CES1CES2CA2CA1MAPT | |
| SCHEMBL14889092 | 0.81 | CES1 (0.52) | CES1CES2CA2CA1MAPT | |
| SCHEMBL28419945 | 0.81 | CES1 (0.52) | CES1CES2BCL2L1BADCA2 | |
| SCHEMBL5466629 | 0.81 | CES2 (0.52) | CES1CES2BCL2L1BADCA2 | |
| SCHEMBL14889160 | 0.80 | ALOX15 (0.50) | CES1CES2CA2CA1NPC1 | |
| SCHEMBL9420249 | 0.80 | LMNA (0.40) | CA2NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL14889163 | 0.80 | ALOX15 (0.50) | CES1CES2CA2CA1NPC1 | |
| SCHEMBL9859948 | 0.79 | CES1 (0.50) | CES1CES2BCL2L1BADCA2 | |
| SCHEMBL2625487 | 0.79 | CES2 (0.54) | CES1CES2BCL2L1BADCA2 | |
| SCHEMBL1716676 | 0.78 | CES1 (0.45) | CES1CES2BCL2L1BADCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011016841-A | PROCESS FOR SYNTHESIZING AZETIDINONE | SCHERING CORP | 2011-01-27 | — | — | JP | disclosed |