Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14889269 | 0.99 | GABRA1 (0.37) | GABRA1GABRB2KDM4ELMNAALB | |
| SCHEMBL14889212 | 0.90 | GABRA1 (0.50) | GABRA1GABRB2KDM4ELMNAALB | |
| Hydrochloric Acid SCHEMBL14889111 | 0.90 | GABRA1 (0.49) | GABRA1GABRB2KDM4ELMNAALB | |
| SCHEMBL14889196 | 0.83 | KDM4E (0.39) | GABRA1GABRB2KDM4ELMNAALB | |
| Hydrochloric Acid SCHEMBL14889270 | 0.83 | KDM4E (0.38) | GABRA1GABRB2KDM4ELMNAALB | |
| SCHEMBL14889213 | 0.73 | GABRB2 (0.52) | GABRA1GABRB2KDM4ELMNAALB | |
| SCHEMBL14899705 | 0.73 | KDM4E (0.52) | GABRA1GABRB2KDM4ELMNAALB | |
| Hydrochloric Acid SCHEMBL14889113 | 0.73 | GABRB2 (0.51) | GABRA1GABRB2KDM4ELMNAALB | |
| Hydrochloric Acid SCHEMBL25412592 | 0.73 | KDM4E (0.52) | GABRA1GABRB2KDM4ELMNAALB | |
| SCHEMBL14889211 | 0.70 | TSPO (0.45) | GABRA1GABRB2KDM4ELMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2586780-B1 | 2-ARYL IMIDAZO[1,2-A]PYRIDINE-3-ACETAMIDE DERIVATIVES, PREPARATION METHODS AND USE THEREOF | INST PHARMACOLOGY & TOXICOLOGY ACAD MILITARY MEDICAL SCIENCES PLA CHINA (CN) | 2017-03-22 | — | — | EP | disclosed |
| EP-2586780-A1 | 2-ARYL IMIDAZO[1,2-A]PYRIDINE-3-ACETAMIDE DERIVATIVES, PREPARATION METHODS AND USE THEREOF | Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China (CN) | 2013-05-01 | — | — | EP | disclosed |