Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1489371 | 1.00 | POLB (0.49) | POLBALDH1A1MAPK1CYP3A4CYP2C9 | |
| SCHEMBL1488968 | 0.91 | POLB (0.54) | POLBALDH1A1MAPK1CYP3A4CYP2C9 | |
| SCHEMBL1488938 | 0.91 | POLB (0.54) | POLBALDH1A1MAPK1CYP3A4CYP2C9 | |
| SCHEMBL1489019 | 0.89 | CES1 (0.49) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1488976 | 0.89 | CES1 (0.49) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1489119 | 0.87 | ALOX5 (0.45) | POLBALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL12830682 | 0.80 | POLB (0.54) | POLBALDH1A1MAPK1CYP3A4CYP2C9 | |
| SCHEMBL12830683 | 0.80 | POLB (0.54) | POLBALDH1A1MAPK1CYP3A4CYP2C9 | |
| SCHEMBL1488869 | 0.80 | CES1 (0.51) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1489203 | 0.80 | CES1 (0.51) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110077305-A1 | 5-LIPOXYGENASE INHIBITORS | FYLOCEL LTD. (GB) | 2011-03-31 | — | — | US | disclosed |
| US-20110077305-A1 | 5-LIPOXYGENASE INHIBITORS | FYLOCEL LTD. (GB) | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077305-A1 | 5-LIPOXYGENASE INHIBITORS | ALOX12, ALOX15, ALOX5 | POLB 1340/4885ALDH1A1 170/4885MAPK1 1536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.