Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1489089 | 1.00 | HDAC1 (0.46) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1489222 | 0.90 | HDAC3 (0.55) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1489223 | 0.90 | HDAC3 (0.55) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1488812 | 0.87 | POLB (0.49) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1488802 | 0.87 | POLB (0.49) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1488813 | 0.87 | POLB (0.49) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1488806 | 0.87 | POLB (0.49) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1489163 | 0.80 | MAPT (0.48) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1489165 | 0.80 | MAPT (0.48) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1489010 | 0.80 | HDAC1 (0.59) | HDAC1HDAC8HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110077305-A1 | 5-LIPOXYGENASE INHIBITORS | FYLOCEL LTD. (GB) | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077305-A1 | 5-LIPOXYGENASE INHIBITORS | ALOX12, ALOX15, ALOX5 | HDAC1 1610/4885HDAC8 2559/4885HDAC3 2267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.