Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.81 |
| ▸ | MAPT | P10636 | 3/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.81 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.81 |
| ▸ | TP53 | P04637 | 1/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.81 |
| ▸ | HPGD | P15428 | 1/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.81 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 1/20 | 0.81 |
| ▸ | BLM | P54132 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9781071 | 1.00 | ALOX5 (0.81) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL10338645 | 1.00 | ALOX5 (0.81) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL9781074 | 1.00 | ALOX5 (0.81) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL6008832 | 0.90 | ALOX5 (0.66) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL6008836 | 0.90 | ALOX5 (0.66) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL6008840 | 0.90 | ALOX5 (0.66) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL7716648 | 0.90 | ALOX5 (1.00) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL2681955 | 0.90 | ALOX5 (1.00) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL2681949 | 0.90 | ALOX5 (1.00) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL9514428 | 0.90 | ALOX5 (1.00) | ALOX5MAPTMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351214-A1 | Anti-inflammatory aryl derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-01-17 | — | — | EP | claimed |
| JP-2088553-A | — | — | None | — | — | JP | disclosed |
| US-20110077305-A1 | 5-LIPOXYGENASE INHIBITORS | FYLOCEL LTD. (GB) | 2011-03-31 | — | — | US | disclosed |
| EP-2299996-A1 | 5-LIPOXYGENASE INHIBITORS | Jackson, William Paul (GB) | 2011-03-30 | — | — | EP | disclosed |
| JP-H0288553-A | ANTI-INFLAMMATORY ARYL DERIVATIVE | WELLCOME FOUND LTD:THE | 1990-03-28 | — | — | JP | disclosed |
| EP-0351214-A1 | Anti-inflammatory aryl derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-01-17 | — | — | EP | disclosed |
| EP-0351214-A1 | Anti-inflammatory aryl derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-01-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077305-A1 | 5-LIPOXYGENASE INHIBITORS | ALOX12, ALOX15, ALOX5 | ALOX5 3/4885MAPT 4880/4885MEN1 3066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.