Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PREP | P48147 | 3/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475715 | 0.87 | PREP (0.67) | ALDH1A1SMN1; SMN2PREPCTRB1TSHR | |
| SCHEMBL205223 | 0.87 | PREP (0.67) | ALDH1A1SMN1; SMN2PREPCTRB1TSHR | |
| SCHEMBL29658848 | 0.87 | PREP (0.67) | ALDH1A1SMN1; SMN2PREPCTRB1TSHR | |
| SCHEMBL29553 | 0.87 | PREP (0.67) | ALDH1A1SMN1; SMN2PREPCTRB1TSHR | |
| Hydrochloric Acid SCHEMBL32677508 | 0.86 | PREP (0.65) | ALDH1A1SMN1; SMN2PREPCTRB1TSHR | |
| SCHEMBL630208 | 0.83 | PREP (0.62) | ALDH1A1SMN1; SMN2PREPCTRB1TSHR | |
| SCHEMBL630241 | 0.83 | PREP (0.62) | ALDH1A1SMN1; SMN2PREPCTRB1TSHR | |
| SCHEMBL82714 | 0.83 | PREP (0.62) | ALDH1A1SMN1; SMN2PREPCTRB1TSHR | |
| SCHEMBL20678314 | 0.82 | PREP (0.71) | ALDH1A1SMN1; SMN2PREPCTRB1TSHR | |
| SCHEMBL17459415 | 0.82 | PREP (0.71) | ALDH1A1SMN1; SMN2PREPCTRB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771021-A2 | NMDA RECEPTOR MODULATORS AND USES THEREOF | North Western University (US) | 2014-09-03 | — | — | EP | disclosed |
| WO-2013063120-A2 | NMDA RECEPTOR MODULATORS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2013-05-02 | — | — | WO | disclosed |