SCHEMBL475715

SCHEMBL475715

O=C(O)[C@H]1CCCN1C(=O)OCc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PREP P48147 3/20 0.67
ALDH1A1 P00352 3/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
CTRB1 P17538 1/20 0.63
NPSR1 Q6W5P4 1/20 0.61
TSHR P16473 2/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
KMT2A Q03164 1/20 0.60
KLK7 P49862 1/20 0.60
KLK5 Q9Y337 1/20 0.60
KDM4E B2RXH2 1/20 0.60
LMNA P02545 1/20 0.60
GFER P55789 1/20 0.59
HSD17B10 Q99714 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29658848 1.00 PREP (0.67) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
SCHEMBL205223 1.00 PREP (0.67) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
SCHEMBL29553 1.00 PREP (0.67) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
Hydrochloric Acid SCHEMBL32677508 0.99 PREP (0.65) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
SCHEMBL630208 0.96 PREP (0.62) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
SCHEMBL82714 0.96 PREP (0.62) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
SCHEMBL630241 0.96 PREP (0.62) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
SCHEMBL18093534 0.95 PREP (0.71) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
SCHEMBL20678314 0.95 PREP (0.71) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
SCHEMBL17459415 0.95 PREP (0.71) PREPALDH1A1SMN1; SMN2CTRB1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-118425362-B Organic acid metabolism marker for distinguishing wild and cultivated four-big domestic fish and application thereof 中国水产科学研究院长江水产研究所 2024-12-10 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-118425362-A Organic acid metabolism marker for distinguishing wild and cultivated four-big domestic fish and application thereof 中国水产科学研究院长江水产研究所 2024-08-02 CN claimed
CN-116514679-A Palladium-catalyzed sp with low-cost and high-efficiency quaternary ammonium nitrate as oxidant 2 And sp (sp) 3 Carbon hydrogen bond alkenylation method 南京工业大学 2023-08-01 CN claimed
CN-108610358-B 3- (trimethylsilyl) pyrrolidine-2-carboxylic acid, intermediate thereof, preparation and application 上海交通大学 2020-08-25 CN claimed
CN-110885358-A Vaccine for preventing tumor recurrence and metastasis and application method thereof 浙江爱睦世医学科技有限公司 2020-03-17 CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 US claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 WO claimed
US-20020037559-A1 PROCESS FOR PRODUCING N-PROTECTED D-PROLINE DERIVATIVES LONZA A.G. (CH) 2002-03-28 US claimed
EP-1005563-A1 METHOD FOR PRODUCING CYCLIC alpha-AMINO ACIDS FREE FROM ENANTIOMERS OR THEIR N-PROTECTED DERIVATIVES BY MEANS OF A D-SPECIFIC AMINOACYLASE Lonza AG (CH) 2000-06-07 EP claimed
WO-1999007873-A1 METHOD FOR PRODUCING CYCLIC α-AMINO ACIDS FREE FROM ENANTIOMERS OR THEIR N-PROTECTED DERIVATIVES BY MEANS OF A D-SPECIFIC AMINOACYLASE LONZA AG (CH) 1999-02-18 WO claimed
WO-2026085629-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF Université de Montréal (CA) 2026-04-30 WO disclosed
US-20260055057-A1 GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF PFIZER INC. (US) 2026-02-26 US disclosed
US-4220587-A BACTERICIDES MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1980-09-02 US disclosed
US-4179437-A Amino acid derivatives of 6-(2-amino-2-arylacetamido) penicillanic acids MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1979-12-18 US disclosed
US-4111932-A BACTERICIDE MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-09-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS PREP 357/4885ALDH1A1 3087/4885SMN1; SMN2 4271/4885
US-20260055057-A1 GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF GIPR, GLP1R, GPR119 PREP 2098/4885ALDH1A1 2197/4885SMN1; SMN2 4001/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS PREP 357/4885ALDH1A1 3087/4885SMN1; SMN2 4271/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS PREP 357/4885ALDH1A1 3087/4885SMN1; SMN2 4271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.