SCHEMBL205223

SCHEMBL205223

O=C(O)C1CCCN1C(=O)OCc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PREP P48147 3/20 0.67
ALDH1A1 P00352 3/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
CTRB1 P17538 1/20 0.63
NPSR1 Q6W5P4 1/20 0.61
TSHR P16473 2/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
KMT2A Q03164 1/20 0.60
KLK7 P49862 1/20 0.60
KLK5 Q9Y337 1/20 0.60
KDM4E B2RXH2 1/20 0.60
LMNA P02545 1/20 0.60
GFER P55789 1/20 0.59
HSD17B10 Q99714 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475715 1.00 PREP (0.67) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
SCHEMBL29658848 1.00 PREP (0.67) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
SCHEMBL29553 1.00 PREP (0.67) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
Hydrochloric Acid SCHEMBL32677508 0.99 PREP (0.65) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
SCHEMBL630208 0.96 PREP (0.62) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
SCHEMBL82714 0.96 PREP (0.62) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
SCHEMBL630241 0.96 PREP (0.62) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
SCHEMBL18093534 0.95 PREP (0.71) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
SCHEMBL20678314 0.95 PREP (0.71) PREPALDH1A1SMN1; SMN2CTRB1NPSR1
SCHEMBL17459415 0.95 PREP (0.71) PREPALDH1A1SMN1; SMN2CTRB1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 553 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112079678-B Method for constructing carboxylic acid or alcohol by olefin remote functionalization 四川大学 2021-12-21 CN claimed
CN-112079678-A Method for constructing carboxylic acid or alcohol by olefin remote functionalization 四川大学 2020-12-15 CN claimed
CN-108610358-B 3- (trimethylsilyl) pyrrolidine-2-carboxylic acid, intermediate thereof, preparation and application 上海交通大学 2020-08-25 CN claimed
EP-0817795-B1 NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR NAEJA PHARMACEUTICAL INC (CA) 2000-11-15 EP claimed
EP-0817795-A1 NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR SYNPHAR LABORATORIES INC. (CA) 1998-01-14 EP claimed
WO-1996032408-A1 NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR SYNPHAR LABORATORIES, INC. (US) 1996-10-17 WO claimed
EP-0384341-A2 New proline derivatives KABUSHIKI KAISHA YAKULT HONSHA (JP) 1990-08-29 EP claimed
US-4434095-A Cyclic analogue of naturally-occurring phagocytosis-stimulant peptide - threonyl-cyclo-[-N.sup.ε -lysyl-prolyl-arginyl] INSTITUTE ORGANICHESKOGO SINTEZA (SU) 1984-02-28 US claimed
JP-55064556-A None JP disclosed
JP-1068396-A None JP disclosed
JP-5271187-A None JP disclosed
US-12625431-B2 EUV resist underlayer film-forming composition NISSAN CHEMICAL CORPORATION (JP) 2026-05-12 US disclosed
US-20250313572-A1 MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE ABBVIE INC (US) 2025-10-09 US disclosed
EP-4494698-A2 INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF Takeda Pharmaceutical Company Limited (JP) 2025-01-22 EP disclosed
US-4179437-A Amino acid derivatives of 6-(2-amino-2-arylacetamido) penicillanic acids MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1979-12-18 US disclosed
US-4111932-A BACTERICIDE MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-09-05 US disclosed
US-4093610-A CYCLIC DODECAPEPTIDE, MULTISTAGE AMERICAN HOME PRODUCTS CORPORATION (US) 1978-06-06 US disclosed
US-4081533-A INHIBITION OF LUTENIZING HORMONE, USING A NONAPEPTIDE, 8-ARGINE-VASOTOCIN, OR A TRIPEPTIDE, PROPYL-ARGINYL-GLYCINAMIDE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1978-03-28 US disclosed
US-3976660-A Pyrrolidine derivatives E. R. SQUIBB & SONS, INC. (US) 1976-08-24 US disclosed
US-3947408-A ANTIANXIETY AGENTS AMERICAN CYANAMID COMPANY (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12625431-B2 EUV resist underlayer film-forming composition EEF1A1, ARF1, EMG1 PREP 4442/4885ALDH1A1 2046/4885SMN1; SMN2 3129/4885
US-20250313572-A1 MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE MCL1, BCL2A1, BCL2L10 PREP 4854/4885ALDH1A1 641/4885SMN1; SMN2 605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.