Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 11/20 | 0.54 |
| ▸ | F2 | P00734 | 8/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16208835 | 0.87 | ALDH1A1 (0.63) | ALDH1A1CYP3A4HSD17B10ROCK1F10 | |
| SCHEMBL14893291 | 0.86 | ALDH1A1 (0.62) | ALDH1A1CYP3A4HSD17B10ROCK1F10 | |
| SCHEMBL14893444 | 0.86 | ALDH1A1 (0.62) | ALDH1A1CYP3A4HSD17B10ROCK1F10 | |
| SCHEMBL14893308 | 0.85 | CYP3A4 (0.69) | ALDH1A1CYP3A4HSD17B10ROCK1F10 | |
| SCHEMBL14895679 | 0.85 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HSD17B10ROCK1F10 | |
| SCHEMBL14893283 | 0.85 | ALDH1A1 (0.54) | ALDH1A1CYP3A4HSD17B10ROCK1F10 | |
| SCHEMBL14893375 | 0.84 | ALDH1A1 (0.60) | ALDH1A1CYP3A4HSD17B10ROCK1F10 | |
| SCHEMBL14893280 | 0.84 | ALDH1A1 (0.54) | ALDH1A1CYP3A4HSD17B10ROCK1F10 | |
| SCHEMBL14893340 | 0.83 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HSD17B10ROCK1F10 | |
| SCHEMBL16208841 | 0.83 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HSD17B10ROCK1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676727-B2 | Myxovirus therapeutics, compounds, and uses related thereto | EMORY UNIVERSITY (US) | 2017-06-13 | — | — | US | disclosed |
| EP-2771324-B1 | MYXOVIRUS THERAPEUTICS, COMPOUNDS, AND USES RELATED THERETO | UNIV EMORY (US) | 2017-02-01 | — | — | EP | disclosed |
| EP-2771324-B1 | MYXOVIRUS THERAPEUTICS, COMPOUNDS, AND USES RELATED THERETO | UNIV EMORY (US) | 2017-02-01 | — | — | EP | disclosed |
| US-9499489-B2 | Myxovirus therapeutics, compounds, and uses related thereto | EMORY UNIVERSITY (US) | 2016-11-22 | — | — | US | disclosed |
| US-9499489-B2 | Myxovirus therapeutics, compounds, and uses related thereto | EMORY UNIVERSITY (US) | 2016-11-22 | — | — | US | disclosed |
| US-20160310511-A1 | Myxovirus Therapeutics, Compounds, and Uses Related Thereto | UNIV EMORY (US) | 2016-10-27 | — | — | US | disclosed |
| US-20140329817-A1 | MYXOVIRUS THERAPEUTICS, COMPOUNDS, AND USES RELATED THERETO | CHILDREN'S HEATLHCARE OF ATLANTA, INC. (US) | 2014-11-06 | — | — | US | disclosed |
| US-20140329817-A1 | MYXOVIRUS THERAPEUTICS, COMPOUNDS, AND USES RELATED THERETO | CHILDREN'S HEATLHCARE OF ATLANTA, INC. (US) | 2014-11-06 | — | — | US | disclosed |
| EP-2771324-A1 | MYXOVIRUS THERAPEUTICS, COMPOUNDS, AND USES RELATED THERETO | Emory University (US) | 2014-09-03 | — | — | EP | disclosed |
| WO-2013063012-A1 | MYXOVIRUS THERAPEUTICS, COMPOUNDS, AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2013-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140329817-A1 | MYXOVIRUS THERAPEUTICS, COMPOUNDS, AND USES RELATED THERETO | RPP30, RNASE1, MAVS | ALDH1A1 1520/4885CYP3A4 2823/4885HSD17B10 2078/4885 |
| US-20160310511-A1 | Myxovirus Therapeutics, Compounds, and Uses Related Thereto | RPP30, MAVS, CXCL10 | ALDH1A1 1827/4885CYP3A4 2867/4885HSD17B10 2097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.