Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.44 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.44 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.44 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.43 |
| ▸ | CPN1 | P15169 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11464663 | 0.82 | LMNA (0.61) | LMNAITGB3ITGA2BF2R | |
| SCHEMBL7315668 | 0.81 | LMNA (0.70) | LMNA | |
| SCHEMBL3923983 | 0.79 | LMNA (0.41) | LMNACHRM3CHRM2CHRM1GABRA5 | |
| SCHEMBL15349789 | 0.79 | LMNA (0.41) | LMNACHRM3CHRM2CHRM1GABRA5 | |
| Hydrochloric Acid SCHEMBL7418852 | 0.78 | TDP1 (0.40) | LMNACHRM3CHRM2CHRM1GABRA5 | |
| Hydrochloric Acid SCHEMBL27418447 | 0.78 | TDP1 (0.40) | LMNACHRM3CHRM2CHRM1GABRA5 | |
| SCHEMBL18030754 | 0.76 | TDP1 (0.39) | LMNACHRM3CHRM2CHRM1GABRA5 | |
| SCHEMBL3344404 | 0.75 | CHRM2 (0.42) | CHRM3CHRM2CHRM1GABRA5GABRB2 | |
| SCHEMBL7420286 | 0.75 | CHRM2 (0.42) | CHRM3CHRM2CHRM1GABRA5GABRB2 | |
| Benzene SCHEMBL3357152 | 0.74 | CHRM3 (0.49) | CHRM3CHRM2CHRM1GABRA5GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013062837-A1 | PIPERIDINE DERIVATIVES USEFUL AS GPR119 AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2013-05-02 | — | — | WO | disclosed |