Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.42 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11464663 | 0.94 | LMNA (0.61) | LMNASLC1A3SLC1A2SLC1A1THRA | |
| SCHEMBL4004096 | 0.90 | LMNA (0.66) | LMNASLC1A3SLC1A2SLC1A1MIF | |
| SCHEMBL1734351 | 0.87 | LMNA (0.62) | LMNASLC1A3SLC1A2SLC1A1MIF | |
| SCHEMBL1735477 | 0.83 | LMNA (0.57) | LMNASLC1A3SLC1A2SLC1A1MIF | |
| SCHEMBL9715628 | 0.82 | LMNA (1.00) | LMNASLC1A3SLC1A2SLC1A1THRA | |
| SCHEMBL13425332 | 0.82 | LMNA (0.58) | LMNASLC1A3SLC1A2SLC1A1MIF | |
| SCHEMBL9208258 | 0.81 | LMNA (0.85) | LMNASLC1A3SLC1A2SLC1A1THRA | |
| SCHEMBL14895668 | 0.81 | LMNA (0.47) | LMNA | |
| SCHEMBL4962640 | 0.81 | LMNA (0.56) | LMNATHRBCYP2D6ALDH1A1KMT2A | |
| SCHEMBL20954311 | 0.80 | LMNA (0.55) | LMNASLC1A3SLC1A2SLC1A1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |