Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.39 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | CPN1 | P15169 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27861417 | 0.98 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HDAC2HDAC1 | |
| SCHEMBL17494202 | 0.88 | SLC6A1 (0.50) | CHRM3GABRA5GABRB2SLC6A1SLC6A12 | |
| SCHEMBL28249888 | 0.88 | SLC6A1 (0.50) | CHRM3GABRA5GABRB2SLC6A1SLC6A12 | |
| SCHEMBL28249924 | 0.88 | SLC6A1 (0.50) | CHRM3GABRA5GABRB2SLC6A1SLC6A12 | |
| SCHEMBL28920884 | 0.85 | ACHE (0.42) | ITGB3ITGA2BF2R | |
| SCHEMBL111361 | 0.84 | — | — | |
| SCHEMBL30427433 | 0.84 | PARP15 (0.42) | CHRM2CHRM1CHRM3TSHRTDP1 | |
| SCHEMBL29991422 | 0.83 | NAAA (0.39) | CHRM2CHRM1CHRM3HDAC2HDAC1 | |
| Hydrochloric Acid SCHEMBL28974199 | 0.82 | — | — | |
| SCHEMBL28479090 | 0.81 | PARP15 (0.38) | CHRM2CHRM1CHRM3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119923391-A | Targeted protein degradation of PARP14 for use in therapy | 艾伯维新加坡运营私人有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-118159530-A | Compounds for the treatment of pain, in particular neuropathic pain and/or other diseases or disorders associated with AT2R and/or AT2R mediated signalling | 康福治疗有限公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2024117789-A1 | PLK1 DEGRADATION INDUCING COMPOUNDS WITH INCREASED RIGIDITY | UPPTHERA, INC. (KR) | 2024-06-06 | — | — | WO | disclosed |
| CN-118076607-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-116615417-B | 1, 4-Diheterocyclic group substituted aromatic ring or aromatic heterocyclic compound and application thereof | 广州必贝特医药股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-117964547-A | Urea compound and application thereof as Sigma2 and 5HT2A dual-target inhibitor | 瀚远医药有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117820199-A | Amide compound and application thereof in preparation of Sigma2 and 5HT2A inhibitors | 瀚远医药有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117820292-A | Quinazolinone derivatives, preparation method and application thereof | 合肥医工医药股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2024067302-A1 | AMIDE COMPOUND AND USE THEREOF IN PREPARATION OF INHIBITOR OF SIGMA2 AND 5HT2A | 瀚远医药有限公司 | 2024-04-04 | — | — | WO | disclosed |
| CN-107207473-A | Compounds having muscarinic receptor antagonist and beta 2 adrenergic receptor agonist activity | 奇斯药制品公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-106103423-A | Chemical compound | 阿斯利康(瑞典)有限公司 | 2016-11-09 | — | — | CN | disclosed |
| EP-3026049-A1 | METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE | Dong-A ST Co., Ltd. (KR) | 2016-06-01 | — | — | EP | disclosed |
| CN-102695506-B | N-piperidinyl acetamide derivatives as calcium channel blockers | NEUROMED PHARMACEUTICALS LTD | 2015-07-22 | — | — | CN | disclosed |
| CN-102933572-B | Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use | HOFFMANN LA ROCHE | 2015-01-07 | — | — | CN | disclosed |
| CN-103442568-A | Furo [3,2-d ] pyrimidine compounds | ABBVIE INC | 2013-12-11 | — | — | CN | disclosed |
| CN-101336244-B | 9-membered heterobicyclic compounds useful as protein kinase inhibitors | ABBOTT LABORATORIES (US) | 2011-11-30 | — | — | CN | disclosed |
| CN-1918172-B | Rifamycin analogs and uses thereof | ACTIVBIOTICS INC | 2011-09-14 | — | — | CN | disclosed |
| WO-2010038901-A1 | 7-PIPERIDINOALKYL-3,4-DIHYDROQUINOLONE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-04-08 | — | — | WO | disclosed |
| CN-1374960-A | novel integrin receptor antagonists | BASF AG (DE) | 2002-10-16 | — | — | CN | disclosed |