Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 6/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131820 | 0.90 | NPBWR1 (0.45) | NPBWR1MCHR1HTR5APOLBSMN1; SMN2 | |
| SCHEMBL14081477 | 0.90 | NPBWR1 (0.44) | NPBWR1MCHR1SMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4137286 | 0.89 | NPBWR1 (0.45) | NPBWR1MCHR1HTR5APOLBSMN1; SMN2 | |
| SCHEMBL17057895 | 0.88 | RAB9A (0.44) | NPBWR1MCHR1POLBSMN1; SMN2NPC1 | |
| SCHEMBL14899875 | 0.88 | NPBWR1 (0.39) | NPBWR1MCHR1POLBSMN1; SMN2NPC1 | |
| SCHEMBL14899899 | 0.83 | USP2 (0.35) | MCHR1LMNAKMT2AALDH1A1HTR6 | |
| SCHEMBL14899777 | 0.80 | NPBWR1 (0.32) | NPBWR1POLBSMN1; SMN2LMNAKMT2A | |
| SCHEMBL14899880 | 0.80 | TP53 (0.42) | NPBWR1MCHR1HTR6 | |
| SCHEMBL14081038 | 0.79 | TP53 (0.48) | NPBWR1MCHR1POLBSMN1; SMN2LMNA | |
| SCHEMBL11946412 | 0.79 | POLB (0.43) | NPBWR1MCHR1POLBLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2586778-A2 | Pyridazinone derivatives useful as glucan synthase inhibitors | Merck Sharp & Dohme Corp. (US) | 2013-05-01 | — | — | EP | disclosed |