Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10190109 | 0.79 | LPAR1 (0.31) | LMNACYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL10203457 | 0.79 | LPAR1 (0.31) | LMNACYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL10203450 | 0.79 | LPAR1 (0.31) | LMNACYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL13398359 | 0.74 | — | — | |
| SCHEMBL8141817 | 0.73 | KDM4E (0.35) | L3MBTL1 | |
| SCHEMBL14042032 | 0.70 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL7688840 | 0.68 | ACHE (0.36) | LMNAALDH1A1PKMMEN1KMT2A | |
| SCHEMBL10896358 | 0.67 | ESR2 (0.32) | CYP2C9MEN1KMT2A | |
| SCHEMBL104009 | 0.65 | — | — | |
| SCHEMBL27836649 | 0.65 | CRBN (0.41) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344483-B1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXOSMITHKLINE IP DEV LTD (GB) | 2013-05-01 | — | — | EP | disclosed |