SCHEMBL14900784

SCHEMBL14900784

CC1NCCNC(C)C(C)NCCNC1C

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALPL P05186 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
FUCA1 P04066 4/20 0.33
MAPT P10636 1/20 0.32
SLC6A2 P23975 1/20 0.32
ADRA1A P35348 1/20 0.32
HTR2B P41595 1/20 0.32
SLC6A3 Q01959 1/20 0.32
FUCA2 Q9BTY2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1190367 1.00
SCHEMBL1190324 1.00
SCHEMBL1190325 1.00
SCHEMBL1190366 1.00
Hydrochloric Acid SCHEMBL30106556 0.96
SCHEMBL8698710 0.89 HIF1A (0.43) ALPLL3MBTL1MAPT
SCHEMBL8698714 0.89 HIF1A (0.43) ALPLL3MBTL1MAPT
SCHEMBL8631773 0.89 HIF1A (0.43) ALPLL3MBTL1MAPT
SCHEMBL8229546 0.89 HIF1A (0.43) ALPLL3MBTL1MAPT
SCHEMBL14407774 0.89 HIF1A (0.43) ALPLL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150196500-A1 Treatment of Mitochondria-Related Diseases and Improvement of Age-Related Metabolic Deficits PHILERA NEW ZEALAND LIMITED (NZ) 2015-07-16 US disclosed
US-20130108709-A1 TREATMENT OF MITOCHONDRIA-RELATED DISEASES AND IMPROVEMENT OF AGE-RELATED METABOLIC DEFICITS PROTEMIX CORPORATION LIMITED (NZ) 2013-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130108709-A1 TREATMENT OF MITOCHONDRIA-RELATED DISEASES AND IMPROVEMENT OF AGE-RELATED METABOLIC DEFICITS TFAM, NDUFAB1, HSPA9 ALPL 3920/4885L3MBTL1 2316/4885FUCA1 3415/4885
US-20150196500-A1 Treatment of Mitochondria-Related Diseases and Improvement of Age-Related Metabolic Deficits TFAM, NDUFAB1, HSPA9 ALPL 3920/4885L3MBTL1 2316/4885FUCA1 3415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.