Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | BAX | Q07812 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975819 | 0.94 | CA12 (0.53) | LTA4HMEN1KMT2AESR1ESR2 | |
| SCHEMBL15800551 | 0.89 | CA12 (0.57) | LTA4HGSTP1CA12CA1CA2 | |
| SCHEMBL14901605 | 0.88 | GSTP1 (0.58) | LTA4HESR1ESR2GSTP1CA12 | |
| SCHEMBL14901604 | 0.83 | NR1H2 (0.50) | LTA4HMEN1KMT2AGSTP1CA12 | |
| SCHEMBL5704167 | 0.82 | CA12 (0.63) | GSTP1CA12CA1CA2CA4 | |
| SCHEMBL12516200 | 0.82 | CYP19A1 (0.54) | ESR1ESR2GSTP1CA12CA1 | |
| SCHEMBL9729724 | 0.82 | LTA4H (0.55) | LTA4HGSTP1CA12CA1CA2 | |
| SCHEMBL14222920 | 0.80 | ESR1 (0.47) | LTA4HMEN1KMT2AESR1ESR2 | |
| SCHEMBL15805612 | 0.80 | ESR1 (0.53) | LTA4HMEN1KMT2AESR1ESR2 | |
| SCHEMBL12516724 | 0.80 | ESR1 (0.53) | LTA4HMEN1KMT2AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9333150-B2 | Dental restorative materials based on polymerizable azides and alkynes | IVOCLAR VIVADENT AG (LI) | 2016-05-10 | — | — | US | disclosed |
| US-20140171536-A1 | Dental Restorative Materials Based on Polymerizable Azides and Alkynes | IVOCLAR VIVADENT AG (LI) | 2014-06-19 | — | — | US | disclosed |
| US-20130109758-A1 | BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-05-02 | — | — | US | disclosed |
| US-20130109758-A1 | BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109758-A1 | BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | SHBG, KLK3, HSD17B11 | LTA4H 2660/4885MEN1 2351/4885KMT2A 1534/4885 |
| US-20140171536-A1 | Dental Restorative Materials Based on Polymerizable Azides and Alkynes | PRXL2A, CNPY2, CDYL | LTA4H 3573/4885MEN1 3577/4885KMT2A 1062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.