SCHEMBL14901648

SCHEMBL14901648

C#CCOc1ccc(C(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
LMNA P02545 1/20 0.53
CYP19A1 P11511 2/20 0.53
CHRNB2 P17787 1/20 0.51
CHRNB4 P30926 1/20 0.51
CHRNA3 P32297 1/20 0.51
CHRNA4 P43681 1/20 0.51
MAOB P27338 2/20 0.47
SCD O00767 1/20 0.47
SRD5A2 P31213 2/20 0.47
NPC1 O15118 1/20 0.46
PARP10 Q53GL7 1/20 0.46
GSTP1 P09211 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
KMT2A Q03164 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12517362 0.91 CYP19A1 (0.59) CYP19A1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL384212 0.86 MAOB (0.56) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL12516200 0.85 CYP19A1 (0.54) LMNACYP19A1CHRNB2CHRNB4CHRNA3
SCHEMBL11529553 0.85 GAA (0.60) ALDH1A1LMNACYP19A1CHRNB2CHRNB4
SCHEMBL16701110 0.85 SRD5A2 (0.57) CYP19A1SCDSRD5A2GSTP1CA12
SCHEMBL25960519 0.84 CYP19A1 (0.57) ALDH1A1CYP19A1CHRNB2CHRNB4CHRNA3
SCHEMBL14901649 0.84 TP53 (0.54) ALDH1A1CYP19A1MAOBKMT2AMEN1
SCHEMBL16364112 0.83 CYP19A1 (0.53) ALDH1A1LMNACYP19A1CHRNB2CHRNB4
SCHEMBL29644530 0.83 CYP19A1 (0.56) ALDH1A1LMNACYP19A1CHRNB2CHRNB4
SCHEMBL26673955 0.83 CYP19A1 (0.56) CYP19A1CHRNB2CHRNB4CHRNA3CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3692101-B1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES ALFA INSTR S R L (IT) 2022-01-12 EP claimed
EP-3692101-A1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES Alfa Instruments S.r.l. (IT) 2020-08-12 EP claimed
WO-2019068935-A1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES ALFA INSTRUMENTS S.R.L. (IT) 2019-04-11 WO claimed
US-20250146186-A1 A METHOD OF PREPARING MULTI-FUNCTIONALIZED CELLULOSE AND USE THEREOF FOR PREPARING MULTI-FUNCTIONALIZED NANOFIBRILLATED CELLULOSE INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (FR) 2025-05-08 US disclosed
EP-4479437-A1 A METHOD OF PREPARING MULTI-FUNCTIONALIZED CELLULOSE AND USE THEREOF FOR PREPARING MULTI-FUNCTIONALIZED NANOFIBRILLATED CELLULOSE Institut National de la Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR) 2024-12-25 EP disclosed
CN-119110812-A Method for producing multifunctional cellulose and use thereof for producing multifunctional nanofibrillated cellulose 法国国家农业、食品和环境研究所 2024-12-10 CN disclosed
WO-2023156348-A1 A METHOD OF PREPARING MULTI-FUNCTIONALIZED CELLULOSE AND USE THEREOF FOR PREPARING MULTI-FUNCTIONALIZED NANOFIBRILLATED CELLULOSE INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (FR) 2023-08-24 WO disclosed
EP-4227323-A1 A METHOD OF PREPARING MULTI-FUNCTIONALIZED CELLULOSE AND USE THEREOF FOR PREPARING MULTI-FUNCTIONNALIZED NANOFIBRILLATED CELLULOSE Institut national de recherche pour l'agriculture, l'alimentation et l'environnement (FR) 2023-08-16 EP disclosed
EP-3692101-B1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES ALFA INSTR S R L (IT) 2022-01-12 EP disclosed
EP-3692101-A1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES Alfa Instruments S.r.l. (IT) 2020-08-12 EP disclosed
WO-2019068935-A1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES ALFA INSTRUMENTS S.R.L. (IT) 2019-04-11 WO disclosed
WO-2018049534-A1 NUCLEOSIDE AND NUCLEOTIDE ANALOGUES BEARING A QUATERNARY ALL-CARBON STEREOGENIC CENTER AT THE 2' POSITION AND METHODS OF USE AS A CARDIOPROTECTIVE AGENT LCB PHARMA INC. (CA) 2018-03-22 WO disclosed
US-20130109758-A1 BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2013-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130109758-A1 BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE SHBG, KLK3, HSD17B11 ALDH1A1 179/4885LMNA 1050/4885CYP19A1 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.