Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4398919 | 0.95 | PKM (0.56) | SRD5A2PKMNR4A2NR4A1NR4A3 | |
| SCHEMBL12517362 | 0.93 | CYP19A1 (0.59) | SRD5A2CYP19A1GSTP1CA12CA1 | |
| SCHEMBL11529553 | 0.90 | GAA (0.60) | SRD5A2CYP19A1GAASCDMAPK1 | |
| SCHEMBL30640594 | 0.88 | CYP19A1 (0.57) | SRD5A2CYP19A1PKMCA1CA2 | |
| SCHEMBL26673845 | 0.88 | CYP19A1 (0.57) | SRD5A2CYP19A1PKMCA1CA2 | |
| SCHEMBL12516200 | 0.86 | CYP19A1 (0.54) | SRD5A2CYP19A1PKMGSTP1CA12 | |
| SCHEMBL29644530 | 0.85 | CYP19A1 (0.56) | SRD5A2CYP19A1NR4A2GSTP1CA12 | |
| SCHEMBL16364112 | 0.85 | CYP19A1 (0.53) | CYP19A1NR4A2GSTP1CA12CA1 | |
| SCHEMBL14901648 | 0.85 | ALDH1A1 (0.53) | SRD5A2CYP19A1GSTP1CA12CA1 | |
| SCHEMBL26673955 | 0.85 | CYP19A1 (0.56) | SRD5A2CYP19A1GSTP1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187342-A1 | METHODS AND COMPOSITIONS FOR DETECTING PROTEIN TARGETS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-09-09 | — | — | WO | disclosed |
| EP-3967260-A1 | LIGHT-ACTUATED FLEXIBLE INSTRUMENT | Karlsruher Institut für Technologie (DE) | 2022-03-16 | — | — | EP | disclosed |
| EP-3512860-B1 | NUCLEOSIDE AND NUCLEOTIDE ANALOGUES BEARING A QUATERNARY ALL-CARBON STEREOGENIC CENTER AT THE 2' POSITION AND METHODS OF USE AS A CARDIOPROTECTIVE AGENT | LCB PHARMA INC (CA) | 2020-11-25 | — | — | EP | disclosed |
| WO-2018049534-A1 | NUCLEOSIDE AND NUCLEOTIDE ANALOGUES BEARING A QUATERNARY ALL-CARBON STEREOGENIC CENTER AT THE 2' POSITION AND METHODS OF USE AS A CARDIOPROTECTIVE AGENT | LCB PHARMA INC. (CA) | 2018-03-22 | — | — | WO | disclosed |
| US-20170307592-A1 | Neuroprotective Chemicals and Methods for Identifying and Using Same | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2017-10-26 | — | — | US | disclosed |
| US-9645139-B2 | Neuroprotective chemicals and methods for identifying and using same | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-05-09 | — | — | US | disclosed |
| US-20170030897-A1 | Neuroprotective Chemicals and Methods for Identifying and Using Same | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2017-02-02 | — | — | US | disclosed |
| US-9243281-B2 | Neuroprotective chemicals and methods for identifying and using same | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-01-26 | — | — | US | disclosed |
| WO-2015070237-A9 | NEUROPROTECTIVE CHEMICALS AND METHODS FOR IDENTIFYING AND USING SAME | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-07-23 | — | — | WO | disclosed |
| WO-2015070237-A1 | NEUROPROTECTIVE CHEMICALS AND METHODS FOR IDENTIFYING AND USING SAME | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-05-14 | — | — | WO | disclosed |
| US-20150132783-A1 | Neuroprotective Chemicals and Methods for Identifying and Using Same | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170307592-A1 | Neuroprotective Chemicals and Methods for Identifying and Using Same | NLN, AIFM1, AIFM2 | SRD5A2 3985/4885CYP19A1 4251/4885PKM 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.