SCHEMBL14902012

SCHEMBL14902012

COc1ccc(N(c2ccc(OC)cc2)c2ccc(-c3ccc(N(c4ccc(OC)cc4)c4ccc(OC)cc4)cc3-c3cc(N(c4ccc(OC)cc4)c4ccc(OC)cc4)ccc3-c3ccc(N(c4ccc(OC)cc4)c4ccc(OC)cc4)cc3C)c(C)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA12 O43570 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
ACHE P22303 1/20 0.38
MEN1 O00255 3/20 0.36
MAPT P10636 3/20 0.36
KMT2A Q03164 3/20 0.36
APP P05067 2/20 0.36
ALDH1A1 P00352 2/20 0.36
SLC2A1 P11166 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13589331 0.95 CA1 (0.42) CA1CA2CA12CA7CA9
SCHEMBL13026514 0.91 CA1 (0.46) CA1CA2CA12CA7CA9
SCHEMBL15499319 0.89 CA12 (0.39) CA1CA2CA12CA7CA9
SCHEMBL12887867 0.86 ABL1 (0.46) CA1CA2CA12CA7CA9
SCHEMBL18330653 0.84 CA1 (0.42) CA1CA2CA12CA7CA9
SCHEMBL18320692 0.84 CA1 (0.42) CA1CA2CA12CA7CA9
SCHEMBL16311437 0.82 ABL1 (0.50) CA1CA2CA12CA7CA9
SCHEMBL11966916 0.82 ACHE (0.47) ACHEMEN1MAPTKMT2AALDH1A1
SCHEMBL3865191 0.82 LMNA (0.45) CA1CA2CA12CA7CA9
SCHEMBL8943599 0.82 LMNA (0.45) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9190617-B2 Photoelectric conversion element and solar cell KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2015-11-17 US disclosed
US-8471143-B2 Photoelectric conversion element and solar cell KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-06-25 US disclosed
US-20130104987-A1 SOLAR CELL WITH ELECTRON INHIBITING LAYER HONEYWELL INTERNATIONAL INC. (US) 2013-05-02 US disclosed