SCHEMBL8943599

SCHEMBL8943599

COc1ccc(N(c2ccc(OC)cc2)c2ccc(C)c(C)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
MAPT P10636 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA12 O43570 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPK1 P28482 1/20 0.44
SIRT5 Q9NXA8 1/20 0.44
ACHE P22303 1/20 0.43
PKM P14618 1/20 0.42
SLC2A1 P11166 1/20 0.40
TUBB1 Q9H4B7 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3865191 1.00 LMNA (0.45) LMNAMAPTL3MBTL1NPC1RAB9A
SCHEMBL13583241 0.94 NPC1 (0.43) LMNAMAPTL3MBTL1NPC1RAB9A
SCHEMBL10057767 0.94 NPC1 (0.43) LMNAMAPTL3MBTL1NPC1RAB9A
SCHEMBL13968214 0.94 ACHE (0.54) LMNAMAPTL3MBTL1NPC1RAB9A
SCHEMBL14523930 0.93 CA4 (0.43) LMNAMAPTL3MBTL1NPC1RAB9A
SCHEMBL10025030 0.90 ACHE (0.48) LMNAMAPTL3MBTL1NPC1RAB9A
SCHEMBL14195419 0.86 ALDH1A1 (0.42) LMNAMAPTL3MBTL1NPC1RAB9A
SCHEMBL13589331 0.86 CA1 (0.42) MAPTRAB9ACA1CA2CA12
SCHEMBL16922638 0.86 RELA (0.62) LMNAACHETUBB1KDM4ETUBB4A
SCHEMBL10066014 0.85 ALDH1A1 (0.42) LMNAMAPTL3MBTL1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629094-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2009-12-08 US disclosed
US-7629094-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2009-12-08 US disclosed
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed