SCHEMBL14902195

SCHEMBL14902195

CCOC(=O)N1CCN(C(=O)CC(C)=O)CC1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
POLB P06746 3/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
HTT P42858 1/20 0.65
KDM4E B2RXH2 2/20 0.54
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
HPGD P15428 1/20 0.53
TSHR P16473 1/20 0.52
MAPT P10636 3/20 0.51
RECQL P46063 1/20 0.51
ABL1 P00519 1/20 0.51
RIN1 Q13671 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
NOS3 P29474 1/20 0.49
NOS2 P35228 1/20 0.49
GAA P10253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13429460 0.83 ALDH1A1 (0.44) ALDH1A1POLBSMN1; SMN2HTTKDM4E
SCHEMBL10985089 0.83 ALDH1A1 (0.72) ALDH1A1POLBSMN1; SMN2HTTKDM4E
SCHEMBL1684895 0.83
SCHEMBL694524 0.82 ALDH1A1 (0.67) ALDH1A1POLBSMN1; SMN2HTTKDM4E
SCHEMBL12847186 0.82 ALDH1A1 (0.71) ALDH1A1POLBSMN1; SMN2HTTKDM4E
SCHEMBL16152216 0.79 ALDH1A1 (0.62) ALDH1A1POLBSMN1; SMN2HTTKDM4E
SCHEMBL26510144 0.79 BLM (0.47) ALDH1A1POLBSMN1; SMN2HTTKDM4E
SCHEMBL1919872 0.79 ALDH1A1 (0.62) ALDH1A1POLBSMN1; SMN2HTTKDM4E
SCHEMBL3334291 0.79 ALDH1A1 (0.62) ALDH1A1POLBSMN1; SMN2HTTKDM4E
SCHEMBL5543470 0.78 ALDH1A1 (0.67) ALDH1A1POLBSMN1; SMN2HTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9943498-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2018-04-17 US disclosed
US-9943498-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2018-04-17 US disclosed
US-20160310459-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias VIFOR (INTERNATIONAL) AG (CH) 2016-10-27 US disclosed
US-20160310459-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias VIFOR (INTERNATIONAL) AG (CH) 2016-10-27 US disclosed
US-9394324-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2016-07-19 US disclosed
US-9394324-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2016-07-19 US disclosed
US-20130109662-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias VIFOR (INTERNATIONAL) AG (CH) 2013-05-02 US disclosed
US-20130109662-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias VIFOR (INTERNATIONAL) AG (CH) 2013-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130109662-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias FECH, SDHB, SLC40A1 ALDH1A1 1539/4885POLB 1821/4885SMN1; SMN2 3363/4885
US-20160310459-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias FECH, SDHB, SLC40A1 ALDH1A1 1539/4885POLB 1821/4885SMN1; SMN2 3363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.