Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122482 | 0.94 | DPP4 (0.35) | KDM4EALDH1A1MAPTTHRBHPGD | |
| SCHEMBL3926851 | 0.93 | DPP4 (0.36) | KDM4EALDH1A1MAPTTHRBHPGD | |
| SCHEMBL2400659 | 0.89 | KDM4E (0.38) | KDM4EALDH1A1MAPTTHRBHPGD | |
| Benzene SCHEMBL7241108 | 0.88 | LMNA (0.31) | KDM4EALDH1A1MAPTTHRBHPGD | |
| SCHEMBL13677583 | 0.85 | HIF1A (0.34) | KDM4EALDH1A1MAPTTHRBHPGD | |
| SCHEMBL13677565 | 0.85 | DPP4 (0.33) | KDM4EALDH1A1MAPTTHRBHPGD | |
| SCHEMBL5097862 | 0.83 | KDM4E (0.40) | KDM4EALDH1A1MAPTTHRBHPGD | |
| SCHEMBL7241102 | 0.83 | GRM2 (0.34) | ALDH1A1SMN1; SMN2L3MBTL1HIF1A | |
| SCHEMBL7269803 | 0.82 | MAPT (0.33) | KDM4EMAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL7126396 | 0.81 | CYP1A2 (0.36) | KDM4EALDH1A1MAPTTHRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130108858-A1 | Methods for Making an Article Coated with a Photochromic Film and Use Thereof in Ophthalmological Optics | Essilor International (Compagnie Generate d Optique (FR) | 2013-05-02 | — | — | US | disclosed |