Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7254413 | 0.91 | HIF1A (0.36) | GRM2ALDH1A1HIF1AABCB11SMN1; SMN2 | |
| Benzene SCHEMBL7241108 | 0.90 | LMNA (0.31) | ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7241920 | 0.88 | MMP9 (0.31) | — | |
| SCHEMBL3926851 | 0.86 | DPP4 (0.36) | ALDH1A1HIF1AL3MBTL1SMN1; SMN2 | |
| SCHEMBL7246685 | 0.85 | RORC (0.36) | — | |
| SCHEMBL2400659 | 0.82 | KDM4E (0.38) | ALDH1A1HIF1AL3MBTL1SMN1; SMN2 | |
| SCHEMBL13677583 | 0.82 | HIF1A (0.34) | ALDH1A1HIF1AL3MBTL1SMN1; SMN2 | |
| SCHEMBL7122482 | 0.81 | DPP4 (0.35) | ALDH1A1HIF1AL3MBTL1SMN1; SMN2BACE1 | |
| Benzene SCHEMBL7254417 | 0.79 | AKR1C3 (0.34) | HIF1AL3MBTL1ABCB11SMN1; SMN2 | |
| SCHEMBL7253577 | 0.79 | MMP9 (0.35) | ALDH1A1HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627121-B1 | Plastic lenses; high optical density on photoactivation; high fatigue resistance; fast decoloration in dark | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2003-09-30 | — | — | US | disclosed |