Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 13/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 13/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14903958 | 0.81 | PDGFRB (0.51) | PDGFRBPDGFRAPSMB5 | |
| SCHEMBL21130363 | 0.80 | PDCD1 (0.58) | PDCD1CD274PDGFRBPDGFRACYP1A2 | |
| SCHEMBL12074044 | 0.78 | PDGFRB (0.72) | PDGFRBPDGFRA | |
| SCHEMBL14903961 | 0.77 | PDCD1 (0.48) | PDCD1CD274VSIRPSMB5CYP1A2 | |
| SCHEMBL14904054 | 0.73 | PDGFRB (0.55) | PDGFRBPDGFRA | |
| SCHEMBL14904333 | 0.72 | PDCD1 (0.51) | PDCD1CD274CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14903983 | 0.72 | PDGFRB (0.54) | PDGFRBPDGFRA | |
| SCHEMBL14926984 | 0.71 | PDCD1 (0.47) | PDCD1CD274CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29558512 | 0.70 | CD274 (1.00) | PDCD1CD274 | |
| SCHEMBL358303 | 0.70 | CD274 (1.00) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102617-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-08-11 | — | — | US | disclosed |
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | RPS4X, RPS4Y1, MRPL21 | PDCD1 4650/4885CD274 4594/4885PDGFRB 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.