SCHEMBL149054

SCHEMBL149054

OC1CCC(CCC2CCC(O)CC2)CC1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
SHBG P04278 1/20 0.38
EPHX2 P34913 1/20 0.33
CHRM2 P08172 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
ALOX5 P09917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10576267 1.00 TSHR (0.41) TSHRSHBGEPHX2CHRM2CHRM1
SCHEMBL796462 0.87 SLC18A3 (0.40) TSHRSHBGEPHX2
SCHEMBL7068277 0.87 SIGMAR1 (0.39) TSHRSHBGEPHX2
SCHEMBL12459792 0.86 PTGS1 (0.33) TSHRSHBG
SCHEMBL10680152 0.86 SHBG (0.41) TSHRSHBGCHRM2CHRM1CHRM3
SCHEMBL10680155 0.86 SHBG (0.41) TSHRSHBGCHRM2CHRM1CHRM3
SCHEMBL25025914 0.84 ESR2 (0.43) TSHRSHBG
SCHEMBL19837778 0.84 ESR2 (0.43) TSHRSHBG
SCHEMBL103167 0.84 ESR2 (0.43) TSHRSHBG
SCHEMBL11212169 0.84 EPHX2 (0.31) TSHRSHBGEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2630181-B1 UNCROSSLINKED, HIGH-FUNCTIONALITY POLYETHEROLS AND THE PREPARATION AND USE THEREOF BASF SE (DE) 2016-09-14 EP claimed
US-8946377-B2 Highly functional polyetherols and the production and use thereof BASF SE (DE) 2015-02-03 US claimed
US-8466250-B2 High-functionality polyetherols and preparation and use thereof BASF SE (DE) 2013-06-18 US claimed
US-20120095162-A1 HIGH-FUNCTIONALITY POLYETHEROLS AND PREPARATION AND USE THEREOF BASF SE (DE) 2012-04-19 US claimed
EP-1017742-A1 THERMOPLASTIC POLYURETHANE ADDITIVES FOR CHAIN EXTENSION AND REACTIVE EXTRUSION EASTMAN CHEMICAL COMPANY (US) 2000-07-12 EP claimed
EP-1017743-A1 THERMOPLASTIC POLYURETHANE ADDITIVES FOR ENHANCING SOLID STATE POLYMERIZATION RATES EASTMAN CHEMICAL COMPANY (US) 2000-07-12 EP claimed
EP-1015516-A1 THERMOPLASTIC POLYURETHANE ADDITIVES FOR IMPROVED POLYMER MATRIX COMPOSITES AND METHODS OF MAKING AND USING THEREFOR EASTMAN CHEMICAL COMPANY (US) 2000-07-05 EP claimed
WO-1999011710-A1 THERMOPLASTIC POLYURETHANE ADDITIVES FOR CHAIN EXTENSION AND REACTIVE EXTRUSION EASTMAN CHEMICAL COMPANY (US) 1999-03-11 WO claimed
WO-1999011711-A1 THERMOPLASTIC POLYURETHANE ADDITIVES FOR ENHANCING SOLID STATE POLYMERIZATION RATES EASTMAN CHEMICAL COMPANY (US) 1999-03-11 WO claimed
WO-1999011712-A1 THERMOPLASTIC POLYURETHANE ADDITIVES FOR IMPROVED POLYMER MATRIX COMPOSITES AND METHODS OF MAKING AND USING THEREFOR EASTMAN CHEMICAL COMPANY (US) 1999-03-11 WO claimed
US-12617892-B2 Application of the ring-opening of uretdiones at low temperature and ambient atmosphere BASF SE (DE) 2026-05-05 US disclosed
US-12428523-B2 Polyurethanes and moisture curable compositions including the same H.B. FULLER COMPANY (US) 2025-09-30 US disclosed
EP-4334372-A1 POLYURETHANES AND MOISTURE CURABLE COMPOSITIONS INCLUDING THE SAME H.B. Fuller Company (US) 2024-03-13 EP disclosed
WO-2023219658-A2 MULTI-LAYERED COATED METAL SUBSTRATES PRC-DESOTO INTERNATIONAL, INC. (US) 2023-11-16 WO disclosed
US-20230323013-A1 APPLICATION OF THE RING-OPENING OF URETDIONES AT LOW TEMPERATURE AND AMBIENT ATMOSPHERE BASF SE (DE) 2023-10-12 US disclosed
US-4535103-A POLYEPOXIDES AND EPOXY RESINS CROSSLINKED AND HARDENED WITH PHOSPHOROUS COMPOUNDS, AMINES, AND DIISOCYANATES ASAHI DENKA KOGYO K.K. (JP) 1985-08-13 US disclosed
US-4530947-A A RUSTY METAL-ADHERING CURABLE MIXTURE OF EPOXIDE-POLYHYDROXIDE REACTION PRODUCT, POLYISOCYANATE AND BITUMINOUS MATERIAL ASAHI DENKA KOGYO K.K. (JP) 1985-07-23 US disclosed
US-4466902-A Rust inhibitor IPPOSHA OIL INDUSTRIES, CO., LTD. (JP) 1984-08-21 US disclosed
US-4340716-A EPOXY RESINS AND HARDENERS ASAHI DENKA KOGYO K.K. (JP) 1982-07-20 US disclosed
US-3950451-A COUPLED PRODUCT OF ALKYLPHENOL AND PHENOL-FORMALDEHYDE-DIAMINE CONDENSATE ASAHI DENKA KOGYO K.K. (JA) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617892-B2 Application of the ring-opening of uretdiones at low temperature and ambient atmosphere UQCRB, SCO2, UTS2R TSHR 4740/4885SHBG 2709/4885EPHX2 640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.