Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.74 |
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.74 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5471062 | 0.89 | TLR7 (0.76) | TLR7TLR8NUDT1 | |
| SCHEMBL31126374 | 0.89 | TLR7 (0.76) | TLR7TLR8NUDT1 | |
| SCHEMBL4311969 | 0.89 | TLR7 (0.76) | TLR7TLR8NUDT1 | |
| SCHEMBL8570489 | 0.89 | TLR7 (0.79) | TLR7TLR8NUDT1 | |
| SCHEMBL24809666 | 0.87 | TLR7 (0.80) | TLR7TLR8NUDT1 | |
| SCHEMBL7837869 | 0.87 | TLR7 (0.72) | TLR7TLR8NUDT1 | |
| SCHEMBL29639773 | 0.87 | TLR7 (0.80) | TLR7TLR8NUDT1 | |
| SCHEMBL22512634 | 0.87 | TLR7 (0.87) | TLR7TLR8NUDT1 | |
| SCHEMBL29639778 | 0.87 | TLR7 (0.87) | TLR7TLR8NUDT1 | |
| SCHEMBL1490511 | 0.86 | TLR7 (0.80) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8598192-B2 | Hydroxylamine substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-12-03 | — | — | US | disclosed |
| US-7968563-B2 | Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-06-28 | — | — | US | disclosed |
| US-7897767-B2 | Oxime substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-01 | — | — | US | disclosed |
| US-20100069427-A9 | Oxime and Hydroxylamine Substituted Imidazo[4,5-c] Ring Compounds and Methods | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2010-03-18 | — | — | US | disclosed |
| EP-1682544-A4 | HYDROXYLAMINE SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2009-05-06 | — | — | EP | disclosed |
| US-20090105295-A1 | HYDROXYLAMINE SUBSTITUTED IMIDAZOQUINOLINES | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-04-23 | — | — | US | disclosed |
| US-20090062328-A1 | Oxime and Hydroxylamine Substituted Imidazo[4,5-c] Ring Compounds and Methods | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-03-05 | — | — | US | disclosed |
| US-20090042925-A1 | OXIME SUBSTITUTED IMIDAZOQUINOLINES | COLEY PHARMACEUTICAL GROUP, INC. | 2009-02-12 | — | — | US | disclosed |
| EP-1685129-A4 | OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2008-10-22 | — | — | EP | disclosed |
| US-20070259881-A1 | Substituted Imidazo Ring Systems and Methods | COLEY PHARMACEUTICAL GROUP, INC. | 2007-11-08 | — | — | US | disclosed |
| EP-1846405-A2 | OXIME AND HYDROXYLAMINE SUBSTITUTED IMIDAZO 4,5-C RING COMPOUNDS AND METHODS | 3M Innovative Properties Company (US) | 2007-10-24 | — | — | EP | disclosed |
| CN-1906192-A | Hydroxylamine substituted imidazo ring compounds | 3M INNOVATIVE PROPERTIES CO (US) | 2007-01-31 | — | — | CN | disclosed |
| CN-1906193-A | Oxime substituted imidazo ring compounds | 3M INNOVATIVE PROPERTIES CO (US) | 2007-01-31 | — | — | CN | disclosed |
| WO-2006086634-A2 | OXIME AND HYDROXYLAMINE SUBSTITUTED IMIDAZO[4,5-C] RING COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-08-17 | — | — | WO | disclosed |
| EP-1685129-A2 | OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M Innovative Properties Company (US) | 2006-08-02 | — | — | EP | disclosed |
| EP-1682544-A2 | HYDROXYLAMINE SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M Innovative Properties Company (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2006009832-A1 | SUBSTITUTED IMIDAZO RING SYSTEMS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-01-26 | — | — | WO | disclosed |
| WO-2005048945-A2 | HYDROXYLAMINE SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-06-02 | — | — | WO | disclosed |
| WO-2005048933-A2 | OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259881-A1 | Substituted Imidazo Ring Systems and Methods | IL2, IL4, IRF3 | TLR7 55/4885TLR8 93/4885NUDT1 606/4885 |
| US-20090105295-A1 | HYDROXYLAMINE SUBSTITUTED IMIDAZOQUINOLINES | IL2, IL4, IFNG | TLR7 54/4885TLR8 140/4885NUDT1 143/4885 |
| US-20100069427-A9 | Oxime and Hydroxylamine Substituted Imidazo[4,5-c] Ring Compounds and Methods | IFNG, IL4, IRF3 | TLR7 76/4885TLR8 110/4885NUDT1 269/4885 |
| US-20090062328-A1 | Oxime and Hydroxylamine Substituted Imidazo[4,5-c] Ring Compounds and Methods | IFNG, IL4, IRF3 | TLR7 76/4885TLR8 110/4885NUDT1 269/4885 |
| US-20090042925-A1 | OXIME SUBSTITUTED IMIDAZOQUINOLINES | IFNG, IL2, IRF3 | TLR7 33/4885TLR8 88/4885NUDT1 997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.