Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.79 |
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.79 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22512634 | 0.91 | TLR7 (0.87) | TLR7TLR8NUDT1 | |
| SCHEMBL29639778 | 0.91 | TLR7 (0.87) | TLR7TLR8NUDT1 | |
| SCHEMBL4311969 | 0.90 | TLR7 (0.76) | TLR7TLR8NUDT1 | |
| SCHEMBL5471062 | 0.90 | TLR7 (0.76) | TLR7TLR8NUDT1 | |
| SCHEMBL31126374 | 0.90 | TLR7 (0.76) | TLR7TLR8NUDT1 | |
| SCHEMBL20080779 | 0.90 | TLR7 (0.77) | TLR7TLR8NUDT1 | |
| SCHEMBL1490576 | 0.89 | TLR7 (0.74) | TLR7TLR8NUDT1 | |
| SCHEMBL25575068 | 0.89 | TLR7 (0.70) | TLR7TLR8NUDT1 | |
| SCHEMBL29481132 | 0.89 | TLR7 (1.00) | TLR7TLR8NUDT1 | |
| SCHEMBL7013310 | 0.89 | TLR7 (1.00) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372511-A1 | ANTIBODY-IMMUNE AGONIST CONJUGATE AND APPLICATIONS THEREOF | GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
| US-11717576-B2 | Antibody-immune agonist conjugate and applications thereof | GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) | 2023-08-08 | — | — | US | disclosed |
| WO-2020205996-A2 | LOCALLY ACTING TOLL-LIKE RECEPTOR 7 (TLR7) AND/OR TLR8 AGONIST IMMUNOTHERAPY COMPOUNDS AND THEIR USES | ALTIMMUNE UK LTD (GB) | 2020-10-08 | — | — | WO | disclosed |
| US-20200316211-A1 | LOCALLY ACTING TOLL-LIKE RECEPTOR 7 (TLR7) AND/OR TLR8 AGONIST IMMUNOTHERAPY COMPOUNDS AND THEIR USES | ALTIMMUNE UK LIMITED (GB) | 2020-10-08 | — | — | US | disclosed |
| US-9884112-B2 | Immunomodulatory agent-polymeric compounds | SELECTA BIOSCIENCES, INC. (US) | 2018-02-06 | — | — | US | disclosed |
| US-20150328300-A1 | IMMUNOMODULATORY AGENT-POLYMERIC COMPOUNDS | SELECTA BIOSCIENCES, INC. (US) | 2015-11-19 | — | — | US | disclosed |
| US-9006254-B2 | Immunomodulatory agent-polymeric compounds | SELECTA BIOSCIENCES, INC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-20140242173-A1 | TARGETED SYNTHETIC NANOCARRIERS WITH PH SENSITIVE RELEASE OF IMMUNOMODULATORY AGENTS | SELECTA BIOSCIENCES, INC. (US) | 2014-08-28 | — | — | US | disclosed |
| US-20140193453-A1 | IMMUNOMODULATORY AGENT-POLYMERIC COMPOUNDS | SELECTA BIOSCIENCES, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| EP-1651190-B1 | FORMULATIONS CONTAINING AN IMMUNE RESPONSE MODIFIER | 3M INNOVATIVE PROPERTIES CO (US) | 2012-09-19 | — | — | EP | disclosed |
| US-20110020388-A1 | TARGETED SYNTHETIC NANOCARRIERS WITH PH SENSITIVE RELEASE OF IMMUNOMODULATORY AGENTS | SELECTA BIOSCIENCES, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| EP-0641342-B1 | ANTIVIRAL 2-ETHYL-1H-IMIDAZO(4,5-C)QUINOLIN-4-AMINES | MINNESOTA MINING & MFG (US) | 1998-08-05 | — | — | EP | disclosed |
| US-5266575-A | Immunomodulator, viricides | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150328300-A1 | IMMUNOMODULATORY AGENT-POLYMERIC COMPOUNDS | CD47, TLR3, IL2 | TLR7 41/4885TLR8 23/4885NUDT1 2241/4885 |
| US-20230372511-A1 | ANTIBODY-IMMUNE AGONIST CONJUGATE AND APPLICATIONS THEREOF | FCGR1A, FCGR2A, TLR3 | TLR7 28/4885TLR8 27/4885NUDT1 3169/4885 |
| US-20200316211-A1 | LOCALLY ACTING TOLL-LIKE RECEPTOR 7 (TLR7) AND/OR TLR8 AGONIST IMMUNOTHERAPY COMPOUNDS AND THEIR USES | TLR7, TLR8, TLR9 | TLR7 1/4885TLR8 2/4885NUDT1 3403/4885 |
| US-20110020388-A1 | TARGETED SYNTHETIC NANOCARRIERS WITH PH SENSITIVE RELEASE OF IMMUNOMODULATORY AGENTS | CD47, IFNG, TSLP | TLR7 31/4885TLR8 36/4885NUDT1 3218/4885 |
| US-11717576-B2 | Antibody-immune agonist conjugate and applications thereof | FCGR1A, FCGR2A, TLR3 | TLR7 28/4885TLR8 27/4885NUDT1 3169/4885 |
| US-20140193453-A1 | IMMUNOMODULATORY AGENT-POLYMERIC COMPOUNDS | CD47, TLR3, IL2 | TLR7 41/4885TLR8 23/4885NUDT1 2241/4885 |
| US-20140242173-A1 | TARGETED SYNTHETIC NANOCARRIERS WITH PH SENSITIVE RELEASE OF IMMUNOMODULATORY AGENTS | CD47, IFNG, TSLP | TLR7 31/4885TLR8 36/4885NUDT1 3218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.