Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14903979 | 0.90 | MTNR1A (0.43) | MTNR1AMTNR1BCYP11B1CYP11B2PDE4A | |
| SCHEMBL12075017 | 0.74 | PDGFRB (0.67) | PDGFRBPDGFRA | |
| SCHEMBL12074908 | 0.72 | ACACA (0.41) | PDGFRBPDGFRA | |
| SCHEMBL16510678 | 0.68 | PDE10A (0.37) | ACHEPDE10APDE3BPDE3A | |
| SCHEMBL14903982 | 0.68 | PDGFRB (0.53) | MTNR1AMTNR1BCYP11B1CYP11B2PDGFRB | |
| SCHEMBL14903974 | 0.67 | PDE4A (0.37) | MTNR1AMTNR1BCYP11B1CYP11B2PDE4A | |
| SCHEMBL12185684 | 0.66 | LTA4H (0.50) | PDE10AGPR55 | |
| SCHEMBL14904027 | 0.66 | PDCD1 (0.39) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL27741326 | 0.65 | PDE4A (0.48) | MTNR1AMTNR1BCYP11B1CYP11B2PDE4A | |
| SCHEMBL12074762 | 0.65 | PDE10A (0.43) | CYP11B1CYP11B2PDGFRBPDGFRAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | RPS4X, RPS4Y1, MRPL21 | MTNR1A 1533/4885MTNR1B 2157/4885CYP11B1 4026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.