Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 14/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907303 | 0.93 | THRB (0.47) | THRBACHETSHR | |
| SCHEMBL12191387 | 0.87 | TSHR (0.53) | THRBACHETSHR | |
| SCHEMBL13309600 | 0.87 | TSHR (0.56) | THRBACHETSHR | |
| SCHEMBL31252941 | 0.87 | THRB (0.53) | THRBACHETSHRALDH1A1 | |
| SCHEMBL15128201 | 0.87 | THRB (0.53) | THRBACHETSHRALDH1A1 | |
| SCHEMBL26935584 | 0.87 | ACHE (0.56) | THRBACHETSHR | |
| SCHEMBL15128212 | 0.86 | THRB (0.51) | THRBACHETSHRALDH1A1 | |
| SCHEMBL12590085 | 0.86 | THRB (0.51) | THRBACHETSHR | |
| SCHEMBL13109227 | 0.86 | THRB (0.51) | THRBACHETSHR | |
| SCHEMBL2696366 | 0.85 | THRB (0.61) | THRBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710113-B2 | Dental composition, kit of parts and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-04-29 | — | — | US | disclosed |
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | KIT, KDM5C, PHAX | THRB 851/4885ACHE 2860/4885TSHR 4041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.