Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 14/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907263 | 0.93 | THRB (0.46) | THRBTSHRACHE | |
| SCHEMBL15128212 | 0.93 | THRB (0.51) | THRBTSHRACHELMNASMN1; SMN2 | |
| SCHEMBL12191387 | 0.92 | TSHR (0.53) | THRBTSHRACHE | |
| SCHEMBL31252941 | 0.91 | THRB (0.53) | THRBTSHRACHELMNASMN1; SMN2 | |
| SCHEMBL15128201 | 0.91 | THRB (0.53) | THRBTSHRACHELMNASMN1; SMN2 | |
| SCHEMBL2407776 | 0.90 | THRB (0.58) | THRBTSHRACHELMNASMN1; SMN2 | |
| SCHEMBL13872027 | 0.90 | THRB (0.58) | THRBTSHRACHELMNASMN1; SMN2 | |
| SCHEMBL22363756 | 0.89 | TSHR (0.58) | THRBTSHRACHE | |
| SCHEMBL13309600 | 0.88 | TSHR (0.56) | THRBTSHRACHE | |
| SCHEMBL13109161 | 0.88 | TSHR (0.47) | THRBTSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710113-B2 | Dental composition, kit of parts and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-04-29 | — | — | US | disclosed |
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | KIT, KDM5C, PHAX | THRB 851/4885TSHR 4041/4885ACHE 2860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.