Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.67 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 3/20 | 0.60 |
| ▸ | HTR1B | P28222 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.60 |
| ▸ | MPO | P05164 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | NQO2 | P16083 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14960996 | 0.94 | MTNR1A (0.63) | MTNR1AMTNR1BTRPV1HTR1AHTR1B | |
| SCHEMBL27084725 | 0.91 | MTNR1A (0.73) | MTNR1AMTNR1BHTR1AHTR1BKMT2A | |
| SCHEMBL30630341 | 0.91 | MTNR1A (0.73) | MTNR1AMTNR1BHTR1AHTR1BKMT2A | |
| SCHEMBL14907359 | 0.91 | MTNR1A (0.74) | MTNR1AMTNR1BTRPV1HTR1AHTR1B | |
| SCHEMBL5616635 | 0.88 | MTNR1A (0.85) | MTNR1AMTNR1BHTR1AKMT2AKDM4E | |
| SCHEMBL17949536 | 0.87 | MTNR1A (0.69) | MTNR1AMTNR1BTRPV1HTR1AHTR1B | |
| SCHEMBL3806527 | 0.87 | MTNR1A (0.68) | MTNR1AMTNR1BTRPV1HTR1AHTR1B | |
| SCHEMBL3815984 | 0.85 | MTNR1A (0.75) | MTNR1AMTNR1BTRPV1HTR1AHTR1B | |
| SCHEMBL12720725 | 0.84 | SPR (0.73) | MTNR1AMTNR1BHTR1AHTR1BKMT2A | |
| SCHEMBL31036086 | 0.83 | MTNR1A (0.87) | MTNR1AMTNR1BTRPV1HTR1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013063492-A1 | NOVEL COMPOSITIONS AND METHODS FOR TREATING CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-05-02 | — | — | WO | disclosed |