Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 4/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 6/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19789519 | 0.85 | PARP10 (0.57) | PARP15PARP10PARP2KMT2AATM | |
| SCHEMBL14907532 | 0.80 | KMT2A (0.46) | KMT2AATMELANEACACBTDP1 | |
| SCHEMBL18253252 | 0.80 | KMT2A (0.46) | KMT2AATMELANEACACBTDP1 | |
| SCHEMBL17433314 | 0.76 | KMT2A (0.43) | KMT2AATMELANEACACBFFAR1 | |
| SCHEMBL9998736 | 0.76 | KMT2A (0.45) | PARP10KMT2AATMELANEACACB | |
| SCHEMBL10890900 | 0.75 | TEAD1 (0.51) | ACACBTDP1 | |
| SCHEMBL31337644 | 0.75 | ALDH1A1 (0.50) | — | |
| SCHEMBL31337642 | 0.75 | ALDH1A1 (0.50) | — | |
| SCHEMBL24709164 | 0.75 | ALDH1A1 (0.55) | KMT2AATMELANETDP1 | |
| SCHEMBL452749 | 0.75 | ELANE (0.56) | PARP10KMT2AATMELANETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771735-B1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |
| US-9507185-B2 | Switch element comprising a liquid crystalline medium | MERCK PATENT GMBH (DE) | 2016-11-29 | — | — | US | disclosed |
| US-9507185-B2 | Switch element comprising a liquid crystalline medium | MERCK PATENT GMBH (DE) | 2016-11-29 | — | — | US | disclosed |
| US-20140293174-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| US-20140293174-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| WO-2013060406-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2013-05-02 | — | — | WO | disclosed |