SCHEMBL14908703

SCHEMBL14908703

CC(C)(C)[C@](CN1C(=O)c2ccccc2C1=O)(OC(N)=O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
ALDH1A1 P00352 4/20 0.41
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
MAPT P10636 2/20 0.39
CHRM2 P08172 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28650967 0.73 CA12 (0.50) CA12CA9ALDH1A1KMT2AMEN1
SCHEMBL6389352 0.72 CA12 (0.49) CA12CA9ALDH1A1KMT2AMEN1
SCHEMBL28655810 0.70 CA12 (0.55) CA12CA9ALDH1A1KMT2AMEN1
SCHEMBL28661067 0.70 CHRM2 (0.45) CA12CA9ALDH1A1KMT2AMEN1
SCHEMBL10507444 0.69 CA12 (0.52) CA12CA9ALDH1A1KMT2AMEN1
SCHEMBL3175482 0.69 CHRM2 (0.49) ALDH1A1RAB9AMAPTCHRM2
SCHEMBL1274681 0.69 CHRM2 (0.49) ALDH1A1RAB9AMAPTCHRM2
SCHEMBL31637536 0.68 MAPK1 (0.42) CA12CA9ALDH1A1KMT2AMEN1
SCHEMBL4374642 0.68 CA12 (0.42) CA12CA9ALDH1A1KMT2AMEN1
SCHEMBL13484325 0.68 ALDH1A1 (0.52) CA12CA9ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2589592-A1 NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF FUJIFILM Corporation (JP) 2013-05-08 EP disclosed