Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110180 | 0.87 | MDM4 (0.73) | MDM4TP53HDAC3HDAC1HDAC2 | |
| SCHEMBL3790102 | 0.82 | NPC1 (0.68) | MDM4TP53HDAC3HDAC1HDAC2 | |
| SCHEMBL19509669 | 0.81 | HDAC3 (0.66) | MDM4TP53HDAC3HDAC1HDAC2 | |
| SCHEMBL6067716 | 0.81 | HDAC1 (0.66) | MDM4TP53HDAC3HDAC1HDAC2 | |
| SCHEMBL10953014 | 0.81 | HDAC3 (0.71) | MDM4TP53HDAC3HDAC1HDAC2 | |
| SCHEMBL10828925 | 0.80 | RAB9A (0.45) | MDM4TP53HDAC3HDAC1HDAC2 | |
| SCHEMBL34933 | 0.80 | TDP1 (0.72) | MDM4TP53HDAC3HDAC1HDAC2 | |
| SCHEMBL1023209 | 0.80 | MAPT (0.83) | MDM4TP53HDAC3HDAC1HDAC2 | |
| SCHEMBL4946074 | 0.79 | NPC1 (0.73) | MDM4TP53HDAC3HDAC1HDAC2 | |
| SCHEMBL6288808 | 0.79 | HDAC3 (0.63) | MDM4TP53HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016233-A1 | PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC CANCER CONTAINING A 5 ALPHA REDUCTASE INHIBITOR AND AN ANTIANDROGEN | MERCK & CO., INC. (US) | 1992-10-01 | — | — | WO | claimed |
| EP-0100051-B1 | NEW DERIVATIVES OF 1-ALKYLAMINE-(4(P-ALKYLOXY-BENZAMIDE)PHENOXY)-2-PROPANOL, HAVING BETA-SYMPATHOLYTIC ACTIVITY, THEIR SALTS, AND PRODUCTION PROCESSES THEREOF | A. Menarini S.a.S. (IT) | 1986-04-09 | — | — | EP | claimed |
| EP-0100051-A1 | New derivatives of 1-alkylamine-(4(p-alkyloxy-benzamide)phenoxy)-2-propanol, having beta-sympatholytic activity, their salts, and production processes thereof | A. Menarini S.a.S. (IT) | 1984-02-08 | — | — | EP | claimed |
| US-8765961-B2 | Near infrared fluorescent imaging agent | FUJIFILM CORPORATION (JP) | 2014-07-01 | — | — | US | disclosed |
| US-20110054188-A1 | NEAR INFRARED FLUORESCENT IMAGING AGENT | FUJIFILM CORPORATION (JP) | 2011-03-03 | — | — | US | disclosed |
| US-20110054181-A1 | NEAR INFRARED FLUORESCENT IMAGING AGENT | FUJIFILM CORPORATION (JP) | 2011-03-03 | — | — | US | disclosed |
| EP-2289563-A1 | Near infrared fluorescent imaging agent | Fujifilm Corporation (JP) | 2011-03-02 | — | — | EP | disclosed |
| EP-2289562-A1 | Near infrared fluorescent imaging agent | Fujifilm Corporation (JP) | 2011-03-02 | — | — | EP | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-0459349-B1 | Silver halide color negative photosensitive material | FUJI PHOTO FILM CO LTD (JP) | 1997-03-26 | — | — | EP | disclosed |
| EP-0294035-B1 | Benzoylaminophenoxybutanoic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5254446-A | Pyrazoloazole magenta coupler; sharpness | FUJI PHOTO FILM CO., LTD. (JP) | 1993-10-19 | — | — | US | disclosed |
| EP-0291245-B1 | BENZOYLAMINOPHENOXYBUTANOIC ACID DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-07-22 | — | — | EP | disclosed |
| EP-0459349-A1 | Silver halide color negative photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-04 | — | — | EP | disclosed |
| EP-0456257-A1 | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-11-13 | — | — | EP | disclosed |
| EP-0294035-A2 | Benzoylaminophenoxybutanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-12-07 | — | — | EP | disclosed |
| EP-0291245-A2 | Benzoylaminophenoxybutanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054181-A1 | NEAR INFRARED FLUORESCENT IMAGING AGENT | MSR1, RXFP1, IK | MDM4 2527/4885TP53 1982/4885HDAC3 786/4885 |
| US-20110054188-A1 | NEAR INFRARED FLUORESCENT IMAGING AGENT | MSR1, IK, RXFP1 | MDM4 2092/4885TP53 1347/4885HDAC3 1157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.