SCHEMBL34933

SCHEMBL34933

O=C(Nc1ccccc1SSc1ccccc1NC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.72
MAPT P10636 3/20 0.72
TP53 P04637 3/20 0.64
MDM4 O15151 2/20 0.64
MDM2 Q00987 1/20 0.64
HDAC3 O15379 1/20 0.59
MAPK1 P28482 1/20 0.59
HDAC1 Q13547 1/20 0.59
HDAC2 Q92769 1/20 0.59
POLB P06746 1/20 0.59
HPGD P15428 1/20 0.59
KMT2A Q03164 4/20 0.58
NPSR1 Q6W5P4 1/20 0.58
HSD17B10 Q99714 1/20 0.58
L3MBTL1 Q9Y468 3/20 0.58
ALDH1A1 P00352 3/20 0.58
GLA P06280 1/20 0.58
CETP P11597 3/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1023209 0.89 MAPT (0.83) TDP1MAPTTP53MDM4MDM2
SCHEMBL28189189 0.87 KMT2A (0.76) TDP1MAPTTP53MDM4MDM2
SCHEMBL6445765 0.86 TDP1 (0.59) TDP1MAPTTP53MDM4MDM2
SCHEMBL13212285 0.86 TP53 (0.79) TDP1MAPTTP53MDM4MDM2
SCHEMBL7722993 0.85 MAPT (0.68) TDP1MAPTTP53MDM4MDM2
SCHEMBL28896841 0.84 TDP1 (1.00) TDP1MAPTTP53MDM4MDM2
SCHEMBL1110180 0.83 MDM4 (0.73) TDP1MAPTTP53MDM4HDAC3
SCHEMBL28277559 0.81 MAPT (0.62) TDP1MAPTTP53MDM4MDM2
SCHEMBL13212300 0.81 ALDH1A1 (0.82) MAPTPOLBKMT2AALDH1A1NPC1
SCHEMBL78295 0.81 TDP1 (0.61) TDP1MAPTTP53MDM4MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 973 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024257830-A1 METHOD FOR PRODUCING AZULENE AND RELATED COMPOUNDS アルプス薬品工業株式会社 2024-12-19 WO claimed
CN-117720735-A Rubber-used compatibilizer, preparation method thereof and heat-resistant rubber material 太原理工大学 2024-03-19 CN claimed
WO-2023103113-A1 METHOD FOR DESULFURIZATION OF WASTE TIRE BY USING SUPERCRITICAL CARBON DIOXIDE 北京工业大学 2023-06-15 WO claimed
CN-115215737-A Method for preparing aldehyde or ketone by selective oxidation of alcohol 嘉兴学院 2022-10-21 CN claimed
CN-113150416-B Shearing aid for processing waste rubber and method for obtaining high-molecular ecological rubber by using shearing aid 三河市长城橡胶有限公司 2022-08-26 CN claimed
CN-110668663-B Iron-sulfur nutrient slow-release ball for biological leaching of sludge heavy metals 太原理工大学 2022-04-05 CN claimed
CN-114031811-A Method for desulfurizing waste tires by using supercritical carbon dioxide 北京工业大学 2022-02-11 CN claimed
CN-113150416-A Shearing aid for processing waste rubber and method for obtaining high-molecular ecological rubber by using shearing aid 三河市长城橡胶有限公司 2021-07-23 CN claimed
CN-110436851-B Noise reduction micro-surfacing with high shear strength and preparation method thereof 山西省交通规划勘察设计院有限公司 2021-07-20 CN claimed
CN-110128723-B Rubber for high-bearing solid tire and preparation method thereof 浙江通超工贸有限公司 2021-06-22 CN claimed
US-5556888-A RUBBER WITH POWDERED VULCANIZED SCRAP RUBBER WITH SURFACE TREATED WITH SWELLING AND VULCANIZATION MAZDA MOTOR CORPORATION (JP) 1996-09-17 US claimed
EP-0711788-A2 Reactive fluoropolymers, process for their manufacture, process for the manufacture of crosslinked, grafted or modified fluoropolymers and use thereof BAYER AG (DE) 1996-05-15 EP claimed
EP-0488231-B1 Sulfur compound-coordinate bonded organic coloring matter, compositions of same, and photorecording media containing same TEIJIN LTD (JP) 1996-05-01 EP claimed
EP-0696613-A1 Preformed, paraffin-containing masticating agent BAYER AG (DE) 1996-02-14 EP claimed
EP-0687707-A1 Preformed, non-agglomerating masticating agent BAYER AG (DE) 1995-12-20 EP claimed
US-5268478-A Radiation resistance to ultraviolet rays TEIJIN LIMITED (JP) 1993-12-07 US claimed
US-5194539-A Of ethylenically unsaturated monomers where the aqueous dispersion is free from odor causing xanthogen disulfide RHONE-POULENC CHIMIE (FR) 1993-03-16 US claimed
EP-0336824-B1 PROCESS FOR PREPARING POLYCHLOROPRENE SOCIETE DISTUGIL (FR) 1992-06-24 EP claimed
EP-0488231-A1 Sulfur compound-coordinate bonded organic coloring matter, compositions of same, and photorecording media containing same TEIJIN LIMITED (JP) 1992-06-03 EP claimed
US-4129538-A EFFECTIVE OVER BROAD RANGE OF TEMPERATURES AMERICAN CYANAMID COMPANY (US) 1978-12-12 US claimed