SCHEMBL1023209

SCHEMBL1023209

O=C(Nc1ccccc1Sc1ccccc1NC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.83
▸ TDP1 Q9NUW8 3/20 0.83
▸ ALDH1A1 P00352 5/20 0.67
▸ L3MBTL1 Q9Y468 4/20 0.67
▸ GLA P06280 1/20 0.67
▸ TP53 P04637 3/20 0.64
▸ MDM4 O15151 2/20 0.64
▸ MDM2 Q00987 1/20 0.64
▸ HPGD P15428 3/20 0.59
▸ POLB P06746 2/20 0.59
▸ HDAC3 O15379 1/20 0.59
▸ MAPK1 P28482 1/20 0.59
▸ HDAC1 Q13547 1/20 0.59
▸ HDAC2 Q92769 1/20 0.59
▸ NPSR1 Q6W5P4 2/20 0.58
▸ KMT2A Q03164 2/20 0.58
▸ HSD17B10 Q99714 1/20 0.58
▸ NPC1 O15118 2/20 0.56
▸ RAB9A P51151 2/20 0.56
▸ CYP1A2 P05177 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28896841 0.91 TDP1 (1.00) MAPTTDP1ALDH1A1L3MBTL1GLA
SCHEMBL34933 0.89 TDP1 (0.72) MAPTTDP1ALDH1A1L3MBTL1GLA
SCHEMBL28189189 0.87 KMT2A (0.76) MAPTTDP1ALDH1A1L3MBTL1TP53
SCHEMBL7722993 0.85 MAPT (0.68) MAPTTDP1ALDH1A1L3MBTL1GLA
SCHEMBL1110180 0.83 MDM4 (0.73) MAPTTDP1TP53MDM4HPGD
SCHEMBL28277559 0.81 MAPT (0.62) MAPTTDP1ALDH1A1L3MBTL1GLA
SCHEMBL1490917 0.80 MDM4 (0.63) MAPTTDP1TP53MDM4MDM2
SCHEMBL6445765 0.79 TDP1 (0.59) MAPTTDP1ALDH1A1L3MBTL1GLA
SCHEMBL4233761 0.79 TDP1 (0.77) MAPTTDP1ALDH1A1L3MBTL1GLA
SCHEMBL13296136 0.79 MAPT (0.58) MAPTTDP1ALDH1A1L3MBTL1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59193939-A — — None — — JP disclosed
EP-2271480-B1 SEALANT MATERIAL COMPOSITION, SELF-SEALING PNEUMATIC TIRE, AND PREPARATION THEREOF CONTINENTAL TIRE THE AMERICAS LLC (US) 2018-10-31 — — EP disclosed
US-8360122-B2 Sealant material composition, self-sealing pneumatic tire, and preparation thereof CONTINENTAL TIRE THE AMERICAS, LLC (US) 2013-01-29 — — US disclosed
EP-2271480-A1 SEALANT MATERIAL COMPOSITION, SELF-SEALING PNEUMATIC TIRE, AND PREPARATION THEREOF Continental Tire North America Inc. (US) 2011-01-12 — — EP disclosed
WO-2009135004-A1 SEALANT MATERIAL COMPOSITION, SELF-SEALING PNEUMATIC TIRE, AND PREPARATION THEREOF CONTINENTAL TIRE NORTH AMERICA, INC (US) 2009-11-05 — — WO disclosed
US-20090272476-A1 SEALANT MATERIAL COMPOSITION, SELF-SEALING PNEUMATIC TIRE, AND PREPARATION THEREOF CONTINENTAL TIRE NORTH AMERICA, INC. (US) 2009-11-05 — — US disclosed
JP-2002103330-A METHOD FOR RECYCLING MATERIAL OF CARPET MAT HIROSHIMA KASEI LTD 2002-04-09 — — JP disclosed
US-5914377-A Method for the production of diene rubbers in the gas phase BAYER AG (DE) 1999-06-22 — — US disclosed
JP-S59193939-A PREPARATION OF FORMED PLASTICIZER KAWAGUCHI KAGAKU KOGYO KK 1984-11-02 — — JP disclosed
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