SCHEMBL14910947

SCHEMBL14910947

Brc1ccc2c(c1)c1cc(Br)ccc1n2-c1cccc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.53
▸ KDM4E B2RXH2 2/20 0.53
▸ ATM Q13315 1/20 0.53
▸ TSPO P30536 3/20 0.43
▸ MEN1 O00255 3/20 0.42
▸ KMT2A Q03164 3/20 0.42
▸ RAD52 P43351 1/20 0.42
▸ DNM1 Q05193 2/20 0.37
▸ ALDH1A1 P00352 2/20 0.37
▸ RXFP1 Q9HBX9 1/20 0.37
▸ MAPT P10636 3/20 0.37
▸ TP53 P04637 1/20 0.37
▸ ACHE P22303 2/20 0.36
▸ LIG1 P18858 1/20 0.36
▸ KRAS P01116 2/20 0.35
▸ HPGD P15428 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ GSK3A P49840 1/20 0.34
▸ GSK3B P49841 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31558734 1.00 L3MBTL1 (0.53) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL14910870 1.00 L3MBTL1 (0.53) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL14910746 1.00 L3MBTL1 (0.53) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL20715071 0.95 L3MBTL1 (0.52) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL14910881 0.93 L3MBTL1 (0.52) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL12156924 0.93 MAPT (0.41) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL16605734 0.92 L3MBTL1 (0.48) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL30032326 0.91 L3MBTL1 (0.67) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL28129746 0.91 L3MBTL1 (0.67) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL261514 0.91 L3MBTL1 (0.67) L3MBTL1KDM4EATMTSPOMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2589643-B1 HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME SK CHEMICALS CO LTD (KR) 2017-09-20 — — EP disclosed
US-9142784-B2 Highly efficient carbazole-based compound, and organic electroluminescence device comprising same SK CHEMICALS CO., LTD. (KR) 2015-09-22 — — US disclosed
US-9142784-B2 Highly efficient carbazole-based compound, and organic electroluminescence device comprising same SK CHEMICALS CO., LTD. (KR) 2015-09-22 — — US disclosed
US-9142784-B2 Highly efficient carbazole-based compound, and organic electroluminescence device comprising same SK CHEMICALS CO., LTD. (KR) 2015-09-22 — — US disclosed
US-20130119367-A1 HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME INDUSTRY ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) 2013-05-16 — — US disclosed
US-20130119367-A1 HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME INDUSTRY ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) 2013-05-16 — — US disclosed
US-20130119367-A1 HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME INDUSTRY ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) 2013-05-16 — — US disclosed
EP-2589643-A2 HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME Industry-Academic Cooperation Foundation, Dankook University (KR) 2013-05-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130119367-A1 HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME PPIP5K2, INPP5B, EZH2 L3MBTL1 1976/4885KDM4E 737/4885ATM 4057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback