Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15428658 | 0.82 | POLB (0.57) | POLBRAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL4951229 | 0.79 | POLB (0.64) | POLBRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL1491089 | 0.79 | POLB (0.64) | POLBRAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL1247688 | 0.79 | POLB (0.64) | POLBRAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL1491132 | 0.79 | POLB (0.58) | POLBRAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL13823006 | 0.79 | POLB (0.58) | POLBRAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL1491081 | 0.79 | POLB (0.58) | POLBRAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL433371 | 0.78 | POLB (1.00) | POLBRAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL1491136 | 0.78 | POLB (0.69) | POLBMAPTSMN1; SMN2KMT2ACYP2C9 | |
| SCHEMBL23130273 | 0.78 | CYP2C9 (0.49) | POLBRAB9ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203435-B1 | 6, 11-BRIDGED BIARYL MACROLIDES | ENANTA PHARM INC (US) | 2018-07-18 | — | — | EP | disclosed |
| WO-2017201683-A1 | SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS USEFUL AS GPR120 AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-11-30 | — | — | WO | disclosed |
| EP-3030560-B1 | BENZIMIDAZOLYL-METHYL UREA DERIVATIVES AS ALX RECEPTOR AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2017-06-21 | — | — | EP | disclosed |
| US-9663473-B2 | Benzimidazolyl-methyl urea derivatives as ALX receptor agonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2017-05-30 | — | — | US | disclosed |
| EP-2788348-B1 | KINASE INHIBITORS | CHIESI FARMA SPA (IT) | 2016-10-19 | — | — | EP | disclosed |
| US-20160200686-A1 | BENZIMIDAZOLYL-METHYL UREA DERIVATIVES AS ALX RECEPTOR AGONISTS | IDORSIA PHARMACEUTICALS LTD (CH) | 2016-07-14 | — | — | US | disclosed |
| CN-103974953-B | Inhibitors of kinases | 奇斯药制品公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-105473575-A | Benzimidazolyl-methylurea derivatives as ALX receptor agonists | ACTELION PHARMACEUTICALS LTD | 2016-04-06 | — | — | CN | disclosed |
| US-9029373-B2 | Kinase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-05-12 | — | — | US | disclosed |
| US-20140343055-A1 | KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A (IT) | 2014-11-20 | — | — | US | disclosed |
| EP-0307817-A1 | Double reacting dyes and benzyl sulfonyl intermediates | BASF Aktiengesellschaft (DE) | 1989-03-22 | — | — | EP | disclosed |
| US-4677199-A | Reactive dyes containing substituted 4-fluoropyridaz-6-one radicals | BASF AKTIENGESELLSCHAFT (DE) | 1987-06-30 | — | — | US | disclosed |
| EP-0119441-B1 | REACTIVE DYES WITH SUBSTITUTED 4-FLUOROPYRIDAZ-6-ONE GROUPS | BASF Aktiengesellschaft (DE) | 1987-02-25 | — | — | EP | disclosed |
| EP-0133270-A1 | Reactive dyes | BASF Aktiengesellschaft (DE) | 1985-02-20 | — | — | EP | disclosed |
| US-4500715-A | CHEMICAL INTERMEDIATES FOR PLANT SAFENING AGENTS AND DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-02-19 | — | — | US | disclosed |
| EP-0119441-A2 | Reactive dyes with substituted 4-fluoropyridaz-6-one groups | BASF Aktiengesellschaft (DE) | 1984-09-26 | — | — | EP | disclosed |
| EP-0031099-B1 | COMPOUNDS WITH REACTIVE RESTS AND THEIR USE IN DYEING FIBRES | BASF Aktiengesellschaft (DE) | 1984-07-18 | — | — | EP | disclosed |
| EP-0031099-A2 | Compounds with reactive rests and their use in dyeing fibres | BASF Aktiengesellschaft (DE) | 1981-07-01 | — | — | EP | disclosed |
| US-4268438-A | Cationic 1,3,4-thiadiazole dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |
| EP-0017768-A1 | Reactive dyestuffs and their use | BASF Aktiengesellschaft (DE) | 1980-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343055-A1 | KINASE INHIBITORS | MAPK1, MAP3K1, MAPK6 | POLB 2524/4885RAB9A 898/4885NPC1 4102/4885 |
| US-20160200686-A1 | BENZIMIDAZOLYL-METHYL UREA DERIVATIVES AS ALX RECEPTOR AGONISTS | UTS2R, ADORA3, P2RX7 | POLB 4087/4885RAB9A 937/4885NPC1 2457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.