Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11769059 | 0.98 | VCAM1 (0.71) | VCAM1ALDH1A1GAAMAPTNPSR1 | |
| SCHEMBL27752714 | 0.85 | TDP1 (0.58) | VCAM1ALDH1A1GAAMAPTNPSR1 | |
| SCHEMBL133996 | 0.85 | VCAM1 (1.00) | VCAM1ALDH1A1GAAMAPTNPSR1 | |
| SCHEMBL6417727 | 0.85 | VCAM1 (1.00) | VCAM1ALDH1A1GAAMAPTNPSR1 | |
| SCHEMBL29510874 | 0.85 | VCAM1 (1.00) | VCAM1ALDH1A1GAAMAPTNPSR1 | |
| SCHEMBL392626 | 0.82 | HPGD (0.62) | VCAM1ALDH1A1GAALMNATDP1 | |
| SCHEMBL550564 | 0.81 | VCAM1 (0.73) | VCAM1ALDH1A1GAAMAPTNPSR1 | |
| Potassium Ion SCHEMBL11769055 | 0.81 | VCAM1 (0.73) | VCAM1ALDH1A1GAAMAPTNPSR1 | |
| SCHEMBL377111 | 0.81 | VCAM1 (0.73) | VCAM1ALDH1A1GAAMAPTNPSR1 | |
| SCHEMBL8195359 | 0.81 | VCAM1 (0.73) | VCAM1ALDH1A1GAAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717053-B | Synthesis method of key intermediate of tyrosine kinase inhibitor | 合肥利夫生物科技有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-113717053-A | Synthesis method of key intermediate of tyrosine kinase inhibitor | 合肥利夫生物科技有限公司 | 2021-11-30 | — | — | CN | claimed |
| CN-101381304-A | Synthetic method of tricaprylin-carboxyl-<13>C3 | SHANGHAI RES INST CHEMICAL IND (CN) | 2009-03-11 | — | — | CN | claimed |
| CN-113717053-B | Synthesis method of key intermediate of tyrosine kinase inhibitor | 合肥利夫生物科技有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-113717053-A | Synthesis method of key intermediate of tyrosine kinase inhibitor | 合肥利夫生物科技有限公司 | 2021-11-30 | — | — | CN | disclosed |
| WO-2019185025-A1 | TRIFLUOROMETHYL-SUBSTITUTED SULFONAMIDE AS BCL-2-SELECTIVE INHIBITOR | 正大天晴药业集团股份有限公司 | 2019-10-03 | — | — | WO | disclosed |
| US-9808527-B2 | Methods and compositions for treating HIV infections | PURDUE RESEARCH FOUNDATION (US) | 2017-11-07 | — | — | US | disclosed |
| US-9095565-B2 | Methods for treating blood disorders | PHOENICIA BIOSCIENCES, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-9095565-B2 | Methods for treating blood disorders | PHOENICIA BIOSCIENCES, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140301975-A1 | Methods for Treating Blood Disorders | PHOENICIA BIOSCIENCES INC (US) | 2014-10-09 | — | — | US | disclosed |
| US-20140301975-A1 | Methods for Treating Blood Disorders | PHOENICIA BIOSCIENCES INC (US) | 2014-10-09 | — | — | US | disclosed |
| EP-0100300-B1 | PROCESS FOR THE POST TREATMENT OF DYED CELLULOSE CONTAINING FIBROUS MATERIALS | CIBA-GEIGY AG (CH) | 1988-06-15 | — | — | EP | disclosed |
| EP-0177978-B1 | NAPHTHOL AMINE DERIVATIVES | BAYER AG (DE) | 1988-04-20 | — | — | EP | disclosed |
| US-4515596-A | Process for aftertreating dyed fibrous material made of or containing cellulose | CIBA-GEIGY CORPORATION (US) | 1985-05-07 | — | — | US | disclosed |
| EP-0100300-A2 | Process for the post treatment of dyed cellulose containing fibrous materials | CIBA-GEIGY AG (CH) | 1984-02-08 | — | — | EP | disclosed |
| US-4051303-A | RECORDING SHEET | FUJI PHOTO FILM CO., LTD. (JA) | 1977-09-27 | — | — | US | disclosed |
| US-4051118-A | Water-soluble disazo dyestuffs containing a 3- or 4-[pyrazolylene-(1)-benzoylamino]-6-sulphophenyl moiety | CIBA-GEIGY AG (CH) | 1977-09-27 | — | — | US | disclosed |
| US-4049656-A | POLYAMIDES AND CELLULOSE | CIBA-GEIGY AG (CH) | 1977-09-20 | — | — | US | disclosed |
| US-4017256-A | FIBER DYEABLE WITH DISPERSE DYES AND FIBER DYEABLE WITH REACTIVE DYES | CIBA-GEIGY CORPORATION (US) | 1977-04-12 | — | — | US | disclosed |
| US-3951588-A | Process for dyeing and printing or optical brightening of cellulose materials | CIBA-GEIGY CORPORATION (US) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140301975-A1 | Methods for Treating Blood Disorders | HBB, HBG1, HBG2 | VCAM1 1431/4885ALDH1A1 642/4885GAA 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.