Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2353943 | 0.82 | SRC (0.50) | SRCALDH1A1L3MBTL1TDP1KDM4E | |
| SCHEMBL28640641 | 0.79 | SRC (0.52) | SRCALDH1A1L3MBTL1TDP1CYP2C9 | |
| SCHEMBL1491262 | 0.79 | SRC (0.52) | SRCALDH1A1L3MBTL1TDP1CYP2C9 | |
| SCHEMBL9372893 | 0.78 | PIN1 (0.46) | SRCALDH1A1L3MBTL1ANPEPLAP3 | |
| Phenyl Dihydrogen Phosphate SCHEMBL11308301 | 0.74 | SRC (0.91) | SRCALDH1A1L3MBTL1TDP1CYP2C9 | |
| Phenyl Dihydrogen Phosphate SCHEMBL20263 | 0.73 | SRC (1.00) | SRCALDH1A1L3MBTL1TDP1CYP2C9 | |
| SCHEMBL6686008 | 0.73 | SRC (0.73) | SRCL3MBTL1TDP1CYP2C9CYP2C19 | |
| SCHEMBL4272051 | 0.73 | SRC (0.73) | SRCL3MBTL1TDP1CYP2C9CYP2C19 | |
| SCHEMBL37038 | 0.73 | SRC (0.73) | SRCALDH1A1L3MBTL1TDP1CYP2C9 | |
| Benzene SCHEMBL11142811 | 0.73 | SRC (0.73) | SRCALDH1A1L3MBTL1TDP1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016074696-A1 | PERFUME INGREDIENTS AND PERFUME PREPARATIONS CONTAINING SAME | GIVAUDAN AG (CH) | 2016-05-19 | — | — | WO | disclosed |
| US-7897635-B2 | HIV protease inhibitors | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-03-01 | — | — | US | disclosed |
| US-20070082883-A1 | HIV protease inhibitors | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-04-12 | — | — | US | disclosed |
| US-7157489-B2 | HIV protease inhibitors | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-01-02 | — | — | US | disclosed |
| EP-1485387-A1 | CARBAMATES AS HIV PROTEASE INHIBITORS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2004-12-15 | — | — | EP | disclosed |
| US-20040039016-A1 | HIV protease inhibitors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-02-26 | — | — | US | disclosed |
| WO-2003078438-A1 | CARBAMATES AS HIV PROTEASE INHIBITORS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2003-09-25 | — | — | WO | disclosed |
| US-6313305-B1 | ANTIBIOTICS, BACTERICIDES | HOECHST MARION ROUSSEL (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-0551034-B1 | Antibiotic cephalosporins having in position 7 a substituted benzyloxyimino radical | HOECHST MARION ROUSSEL INC (FR) | 2000-09-20 | — | — | EP | disclosed |
| EP-1016646-A1 | Intermediates for the preparation of cephalosporines containing on the 7-position a substituted benzyloximino radical | HOECHST MARION ROUSSEL (FR) | 2000-07-05 | — | — | EP | disclosed |
| US-5883248-A | QUATERNARY AMMONIUM INTERMEDIATES | ROUSSEL UCLAF (FR) | 1999-03-16 | — | — | US | disclosed |
| US-5763617-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5728828-A | A 3-(3-CHLORO- OR IODOPROP-1-EN-1-YL),7-(2-AMINOTHIAZOL-4-YL) ((CARBOXY)(PHENYL)METHOXYIMINO)ACETAMIDO-3-CEPHEM; GRAMNEGATIVE AND -POSITIVE BACTERIA, ESP. ANTIBIOTIC-RESISTANCE STAPHYLOCOCCUS | ROUSSEL UCLAF (FR) | 1998-03-17 | — | — | US | disclosed |
| US-5712266-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-01-27 | — | — | US | disclosed |
| US-5587372-A | BACERICIDES | ROUSSEL UCLAF (FR) | 1996-12-24 | — | — | US | disclosed |
| US-5455238-A | Bactericides | ROUSSEL UCLAF (FR) | 1995-10-03 | — | — | US | disclosed |
| EP-0551034-A2 | Cephalosporins having in position 7 a benzyloxyimino radical substitute, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1993-07-14 | — | — | EP | disclosed |
| US-4599330-A | 24,24-DIFLUORO-1,25-DIHYDROXYCHOLECALCIFEROL | HOFFMANN-LA ROCHE INC. (US) | 1986-07-08 | — | — | US | disclosed |
| US-4421690-A | ANTI-RACHITOGENIC | HOFFMANN-LA ROCHE INC. (US) | 1983-12-20 | — | — | US | disclosed |
| US-4397847-A | OF OSTEOPOROSIS WITH 24,24-DIFLUORO-1,25-DIHYDROXYCHOLECALCIFEROL | HOFFMANN-LA ROCHE INC. (US) | 1983-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082883-A1 | HIV protease inhibitors | SERPINB1, TMPRSS15, DNPEP | SRC 3633/4885ALDH1A1 2558/4885L3MBTL1 898/4885 |
| US-20040039016-A1 | HIV protease inhibitors | SERPINB1, TMPRSS15, DNPEP | SRC 3633/4885ALDH1A1 2558/4885L3MBTL1 898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.