SCHEMBL1491293

SCHEMBL1491293

C#CCOCCOCCOCCOCCOCCOCCOCCOCCN

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4122804 1.00 TSHR (0.40) TSHR
SCHEMBL31616404 1.00 TSHR (0.40) TSHR
SCHEMBL563252 1.00 TSHR (0.40) TSHR
SCHEMBL30724855 1.00 TSHR (0.40) TSHR
SCHEMBL2552181 1.00 TSHR (0.40) TSHR
SCHEMBL18237339 1.00 TSHR (0.40) TSHR
SCHEMBL18089434 1.00 TSHR (0.40) TSHR
Hydrochloric Acid SCHEMBL25375836 0.97 TSHR (0.39) TSHR
SCHEMBL2818899 0.95
Hydrochloric Acid SCHEMBL25377147 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025120219-A2 NOVEL POLYPEPTIDES ONCOPEPTIDES INNOVATION 1 AB (SE) 2025-06-12 WO disclosed
US-20250127913-A1 BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS LYCIA THERAPEUTICS, INC. 2025-04-24 US disclosed
US-12084517-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells YALE UNIVERSITY (US) 2024-09-10 US disclosed
US-12042542-B2 Synthetic antibody mimetic compounds (SYAMS) targeting cancer, especially prostate cancer YALE UNIVERSITY (US) 2024-07-23 US disclosed
US-20240165250-A1 Bifunctional Folate Receptor Binding Compounds LYCIA THERAPEUTICS, INC. 2024-05-23 US disclosed
US-20240156972-A1 ANTIBODY RECRUITMENT MOLECULES AND METHODS OF TREATING CANCER USING SAME MCMASTER UNIVERSITY (CA) 2024-05-16 US disclosed
EP-4359414-A1 BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS Lycia Therapeutics, Inc. (US) 2024-05-01 EP disclosed
US-20240067756-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS UNIV YALE (US) 2024-02-29 US disclosed
US-20240067756-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS UNIV YALE (US) 2024-02-29 US disclosed
EP-4298131-A1 ANTIBODY RECRUITMENT MOLECULES AND METHODS OF TREATING CANCER USING SAME McMaster University (CA) 2024-01-03 EP disclosed
EP-2991677-A1 SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPECIALLY PROSTATE CANCER Yale University (US) 2016-03-09 EP disclosed
WO-2014178878-A1 SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPECIALLY PROSTATE CANCER YALE UNIVERSITY (US) 2014-11-06 WO disclosed
US-8859509-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells YALE UNIVERSITY (US) 2014-10-14 US disclosed
US-8859509-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells YALE UNIVERSITY (US) 2014-10-14 US disclosed
US-8852630-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells YALE UNIVERSITY (US) 2014-10-07 US disclosed
US-20120034295-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS YALE UNIVERSITY 2012-02-09 US disclosed
US-20110201563-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS YALE UNIVERSITY (US) 2011-08-18 US disclosed
US-20110201563-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS YALE UNIVERSITY (US) 2011-08-18 US disclosed
EP-2291659-A2 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS Yale University, Inc. (US) 2011-03-09 EP disclosed
WO-2009139863-A2 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS YALE UNIVERSITY (US) 2009-11-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120034295-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS BRDT, PAICS, KLK3 TSHR 4176/4885
US-20240156972-A1 ANTIBODY RECRUITMENT MOLECULES AND METHODS OF TREATING CANCER USING SAME HAVCR2, CD40LG, CD81 TSHR 3500/4885
US-20250127913-A1 BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS FOLR1, FOLR2, FOLH1 TSHR 137/4885
US-20110201563-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS BRDT, PAICS, KLK3 TSHR 4176/4885
US-20240165250-A1 Bifunctional Folate Receptor Binding Compounds FOLR1, FOLR2, FOLH1 TSHR 137/4885
US-20240067756-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS BRDT, PAICS, KLK3 TSHR 4176/4885
US-12084517-B2 Chimeric small molecules for the recruitment of antibodies to cancer cells BRDT, PAICS, KLK3 TSHR 4176/4885
US-12042542-B2 Synthetic antibody mimetic compounds (SYAMS) targeting cancer, especially prostate cancer CD47, FCGR1A, FCGR2A TSHR 1021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.