SCHEMBL18237339

SCHEMBL18237339

C#CCOCCOCCOCCOCCOCCOCCN

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4122804 1.00 TSHR (0.40) TSHR
SCHEMBL31616404 1.00 TSHR (0.40) TSHR
SCHEMBL563252 1.00 TSHR (0.40) TSHR
SCHEMBL30724855 1.00 TSHR (0.40) TSHR
SCHEMBL1491293 1.00 TSHR (0.40) TSHR
SCHEMBL2552181 1.00 TSHR (0.40) TSHR
SCHEMBL18089434 1.00 TSHR (0.40) TSHR
Hydrochloric Acid SCHEMBL25375836 0.97 TSHR (0.39) TSHR
SCHEMBL2818899 0.95
Hydrochloric Acid SCHEMBL25377147 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025133234-A1 SORTILIN BINDERS AND BIFUNCTIONAL COMPOUNDS THEREOF DRAUPNIR BIO APS (DK) 2025-06-26 WO disclosed
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
US-20250002526-A1 PHARMACEUTICAL COMPOSITION HAVING ANTI-CANCER IMMUNOSTIMULATING EFFECT AND/OR IMMUNE CHECKPOINT INHIBITION POTENTIATING EFFECT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2025-01-02 US disclosed
EP-4420666-A1 PHARMACEUTICAL COMPOSITION HAVING ANTI-CANCER IMMUNOSTIMULATING EFFECT AND/OR IMMUNE CHECKPOINT INHIBITION POTENTIATING EFFECT Kyushu University, National University Corporation (JP) 2024-08-28 EP disclosed
US-20240165250-A1 Bifunctional Folate Receptor Binding Compounds LYCIA THERAPEUTICS, INC. 2024-05-23 US disclosed
CN-117460507-A Compound targeting fibroblast activation protein and method of use thereof 普渡研究基金会 2024-01-26 CN disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed
WO-2023225369-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR CELL-SPECIFIC PHARMACOLOGY DUKE UNIVERSITY (US) 2023-11-23 WO disclosed
EP-4274619-A1 BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS Lycia Therapeutics, Inc. (US) 2023-11-15 EP disclosed
US-20230190939-A1 ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF INTOCELL, INC. (KR) 2023-06-22 US disclosed
US-20190111142-A1 Silanol Based Therapeutic Payloads BLINKBIO, INC. (US) 2019-04-18 US disclosed
US-20180200273-A1 Silanol Based Therapeutic Payloads BLINKBIO INC (US) 2018-07-19 US disclosed
US-9931407-B2 Silicon based drug conjugates and methods of using same BLINKBIO, INC. (US) 2018-04-03 US disclosed
US-9931407-B2 Silicon based drug conjugates and methods of using same BLINKBIO, INC. (US) 2018-04-03 US disclosed
US-9931407-B2 Silicon based drug conjugates and methods of using same BLINKBIO, INC. (US) 2018-04-03 US disclosed
WO-2017214491-A1 SILANOL BASED THERAPEUTIC PAYLOADS BLINKBIO, INC. (US) 2017-12-14 WO disclosed
US-20170202970-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME BLINKBIO, INC. 2017-07-20 US disclosed
US-20170202970-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME BLINKBIO, INC. 2017-07-20 US disclosed
US-20170202970-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME BLINKBIO, INC. 2017-07-20 US disclosed
WO-2016183359-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME BLINKBIO, INC. (US) 2016-11-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190939-A1 ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF CD47, ENPP2, CD2 TSHR 823/4885
US-20170202970-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME CD44, MSN, AS3MT TSHR 2393/4885
US-20250002526-A1 PHARMACEUTICAL COMPOSITION HAVING ANTI-CANCER IMMUNOSTIMULATING EFFECT AND/OR IMMUNE CHECKPOINT INHIBITION POTENTIATING EFFECT CD274, PDCD1, PDCD1LG2 TSHR 942/4885
US-20180200273-A1 Silanol Based Therapeutic Payloads CD47, CD4, BST2 TSHR 3437/4885
US-20190111142-A1 Silanol Based Therapeutic Payloads CD47, CD4, BST2 TSHR 3437/4885
US-20240165250-A1 Bifunctional Folate Receptor Binding Compounds FOLR1, FOLR2, FOLH1 TSHR 137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.