SCHEMBL1491583

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12660767	0.92	HDAC1 (0.46)	HDAC1HDAC8HDAC3HDAC4HDAC7
	SCHEMBL12672779	0.89	HDAC1 (0.43)	HDAC1HDAC8HDAC3HDAC4HDAC7
	SCHEMBL12673064	0.89	HDAC1 (0.61)	HDAC1HDAC8HDAC3HDAC4HDAC7
	SCHEMBL1491439	0.88	HDAC1 (0.65)	HDAC1HDAC8HDAC3HDAC4HDAC7
	SCHEMBL1491585	0.75	CTSL (0.38)	HDAC1HDAC6CTSLITGB3ITGA2B
	SCHEMBL1893680	0.74	HDAC1 (1.00)	HDAC1HDAC8HDAC3HDAC4HDAC7
	SCHEMBL5808207	0.74	HDAC1 (0.55)	HDAC1HDAC8
	SCHEMBL8258867	0.74	HDAC1 (0.55)	HDAC1HDAC8
	SCHEMBL8259003	0.73	HDAC1 (0.60)	HDAC1HDAC8HDAC3HDAC4HDAC7
	SCHEMBL12660735	0.72	CTSL (0.55)	HDAC1HDAC8HDAC3HDAC2HDAC10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.