Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | TYK2 | P29597 | 3/20 | 0.51 |
| ▸ | JAK2 | O60674 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATR | Q13535 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14917439 | 0.90 | ROCK2 (0.66) | PRKCIHTTROCK2ROCK1TYK2 | |
| SCHEMBL14917435 | 0.89 | ALDH1A1 (0.61) | PRKCIHTTNAMPTALDH1A1KDM4E | |
| SCHEMBL6616374 | 0.82 | MEN1 (0.65) | HTTROCK2ROCK1TYK2JAK2 | |
| SCHEMBL4782636 | 0.81 | HTT (0.67) | HTTROCK2ROCK1TYK2JAK2 | |
| SCHEMBL460200 | 0.80 | PRKCI (0.67) | PRKCIHTTTYK2JAK2ALDH1A1 | |
| SCHEMBL30339468 | 0.80 | PRKCI (0.67) | PRKCIHTTTYK2JAK2ALDH1A1 | |
| SCHEMBL14917446 | 0.80 | NPC1 (0.67) | ALDH1A1KDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9197573 | 0.79 | ROCK2 (0.79) | HTTROCK2ROCK1TYK2JAK2 | |
| SCHEMBL30505228 | 0.79 | ALDH1A1 (0.70) | PRKCIHTTNAMPTALDH1A1KDM4E | |
| SCHEMBL2771906 | 0.79 | ALDH1A1 (0.70) | PRKCIHTTNAMPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023231996-A1 | CRYSTAL FORMS OF HYDROXAMIC ACID ESTER COMPOUND AND SALT THEREOF, AND PREPARATION METHOD | 深圳微芯生物科技股份有限公司 | 2023-12-07 | — | — | WO | disclosed |
| US-8895585-B2 | Nicotinamide derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2014-11-25 | — | — | US | disclosed |
| US-8809371-B2 | — | — | 2014-08-19 | — | — | US | disclosed |
| US-8772320-B2 | — | — | 2014-07-08 | — | — | US | disclosed |
| US-20130116430-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116430-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | SYK, CD38, BTK | PRKCI 748/4885HTT 2347/4885ROCK2 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.